Facing some challenges during your coating process – Overwetting
Film coating agents for tablet medications
Tablets are among the most commonly used forms for oral administration. Film coating is the final step in tablet manufacturing. It is used to:
- Protect cores from external aggression with a physical barrier
- Protect hygroscopic cores from humidity
- Modulate the release of the active ingredient
- Color tablets to facilitate identification
- Improve therapeutic adherence by facilitating drug intake (swallowing) and by masking the intrinsic active ingredient characteristics (taste, color, odor…)
We, Seppic, offer multiple ranges of ready-to-use, immediate release, and functional film coating agents. Read on to find out more about the characteristics of our film-coating agents!
Discover the causes and some solutions to overcome them:
OVERWETTING
You observed that the tablets are sticky, decolorated in some areas and the film is pulling-out?
Main causes:
- Tablet bed temperature too low
- Non efficient drying
- Nozzles too close to the tablet
- Unadapted coating formula / sticky formula
Main solutions:
Tablet bed temperature too low / Non efficient drying
- Reduce spray-rate
- Increase inlet air temperature
- Increase pan speed
Nozzles too close to tabley bed
- Increase nozzles/tablet bed distance
Sticky coating formula
- Modify the coating formula
Want to know more about overwetting, watch our video:
How to identify and solve overwetting troubleshooting. Discover our expertise on film coating agents for tablet medications.
See the full brochure on “Overwetting” here
(click the picture to download the brochure)
Source: Seppic brochure “Overwetting”