Viatel Ultrapure

Description

Viatel™ Ultrapure polymers are high-purity, controlled release polymers that provide improved release consistency and extended-release durations; they are better suited for sensitive drug compounds in long acting injectables and implants (LAII). Removing residual monomer reduces acidic equivalents and results in a more consistent rate of water uptake and degradation kinetics. This means more reproducible performance while also creating a more neutral pH environment. Viatel™ Ultrapure polymers leverage a proprietary purification process that reduces total residual monomer content specifications to below 0.5% with typical batch results of approximately 0.1%. Furthermore, these polymers are pre-filtered during the purification process to ensure exceptional quality.

These low-monomer products are available as GMP grades across the Viatel™ platform and provide formulators greater versatility when solving challenging formulation problems.

Viatel™ Ultrapure polymers are the result of Ashland’s commitment to continuous improvement in response to customer needs.

 

key features

• lowered residual monomer content: ≤ 0.5% total, typical batch results of 0.1%
• reduced tin content (catalyst) is available upon request
• pre-filtered polymer to remove risk of impurities or foreign particles

benefits

• reduced acidity leading to improved stability of sensitive drug compounds
• improved release consistency across all applications due to fewer variables
• extended release with hot melt extrusion applications
• faster solubilization in organic solvents

applications

• LAII products, such as microspheres, in-situ depots, implants, and nanoparticle