The absorption of orally administered drug products is a complex, dynamic process, dependent on a range of biopharmaceutical properties; notably the aqueous solubility of a molecule, stability within the gastrointestinal tract (GIT) and…

An important goal of the European Cooperation in Science and Technology (COST) Action UNGAP (UNderstanding Gastrointestinal Absorption-related Processes, www.ungap.eu) is to improve standardization of methods relating to the study of oral…

The absorption of oral drugs is frequently plagued by significant variability with potentially serious therapeutic consequences. The source of variability can be traced back to interindividual variability in physiology, differences in…

Although oral drug delivery is the preferred administration route and has been used for centuries, modern drug discovery and development pipelines challenge conventional formulation approaches and highlight the insufficient mechanistic…

An UNGAP video further focussing on specific intraluminal behavior of advanced formulations such as supersaturating drug delivery systems, nanoparticles, and lipid-based and controlled release formulations. About Oral…

Oral administration is the most common route of drug delivery. The absorption of a drug from the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of the active pharmaceutical ingredient and its…

You have you missed the most popluar articles of this week? No worries you will find them here. We also include the top phama excipient pages of last month and the most popular posts of the current year. This might give some hints which…

In this excellent review article issued from the UNGAP program (European Network on Understanding Gastro-intestinal Absorption-related Process) you will find relevant and up-to-date information on: - Poorly water soluble drugs and the link…