Browsing Category
antimicrobial
Development of emulgel formulation from Markhamia tomentosa leaf extract: Characterization and in…
Abstract
Objectives:
Skin infections are mild to severe infections often treated with antimicrobial agents. There is an increase in resistance to antimicrobial agents necessitating the search for new medicines. This study developed an emulgel formulation of Markhamia tomentosa leaf extract and…
Read More...
Read More...
How oregano essential oil can be transformed into a taste-masking controlled release solid…
Oregano essential oil (OEO) has antioxidant, antiproliferative, anti-inflammatory and antimicrobial activities. OEO could be administered orally for some gastrointestinal diseases, however, its oral use, is severely hampered by its irritant taste, which requires a high dilution in water before…
Read More...
Read More...
Therapeutic Potential of Nanocarrier Mediated Delivery of Peptides for Wound Healing: Current…
Wound healing presents a complex physiological process that involves a sequence of events orchestrated by various cellular and molecular mechanisms. In recent years, there has been growing interest in leveraging nanomaterials and peptides to enhance wound healing outcomes. Nanocarriers offer unique…
Read More...
Read More...
QbD Based Formulation Development and Optimisation of Ozenoxacin Topical Nano-Emulgel and Efficacy…
To formulate and optimize Ozenoxacin nano-emulsion using Quality by Design (QbD) concept by means of Box–Behnken Design (BBD) and converting it to a gel to form Ozenoxacin nano-emulgel followed by physico-chemical, in-vitro, ex-vivo and in-vivo evaluation. This study demonstrates the application of…
Read More...
Read More...
Enhanced mechanical and antimicrobial properties of hydroxypropyl methylcellulose films…
In this study, we produced hydroxypropyl methylcellulose (HPMC) films containing silver nanoparticles (AgNPs) by a straightforward method for potential wound dressing applications. Polyvinylpyrrolidone (PVP) or polyvinyl alcohol (PVA) was added to these films to improve their mechanical properties.…
Read More...
Read More...
A review on natural biopolymers in external drug delivery systems for wound healing and atopic…
Abstract
Despite the advantages of topical administration in the treatment of skin diseases, current marketed preparations face the challenge of the skin's barrier effect, leading to low therapeutic effectiveness and undesirable side effects. Hence, in recent years the management of skin wounds,…
Read More...
Read More...
Development of a Eudragit-based hydrogel for the controlled release of hydrophobic and hydrophilic…
Wounds are a daily occurrence that requires wound dressings to prevent infections and promote healing. Various wound dressing types are used in clinics to prevent infections and promote healing, and dressings vary with the wound's severity and complexity. Hydrogel-based wound dressing offers several…
Read More...
Read More...
Freeze-Drying of Encapsulated Bacteriophage T4 to Obtain Shelf-Stable Dry Preparations for Oral…
Therapeutic application of bacterial viruses (phage therapy) has in recent years been rediscovered by many scientists, as a method which may potentially replace conventional antibacterial strategies. However, one of the main problems related to phage application is the stability of bacterial…
Read More...
Read More...
Buccal delivery system of active pharmaceutical ingredients-ionic liquid (API-IL): Effects of API-IL…
Ionic liquid (IL) salt of active pharmaceutical ingredient (API) represents a promising formulation strategy to address low drug solubility and polymorphism prevalent in API solid crystals. The present work developed for the first time a buccal delivery system of API-IL via fast-dissolving…
Read More...
Read More...
A Novel Handrub Tablet Loaded with Pre- and Post-Biotic Solid Lipid Nanoparticles Combining…
Objective:
This study aimed to develop a holobiont tablet with rapid dispersibility to provide regulation of the microbiota, virucidal activity, and skin barrier protection.
Methods:
A 23 factorial experiment was planned to define the best formulation for the development of the base tablet,…
Read More...
Read More...