Browsing Category
antimicrobial
Smart nano-in-microparticles to tackle bacterial infections in skin tissue engineering
Chronic wounds (resulting from underlying disease, metabolic disorders, infections, trauma, and even tumours) pose significant health problems. In this work, microparticles, based on polysaccharides (maltodextrin or dextran) and amino acids, and doped with antibacterial nanoparticles (CuO or ZnO…
Read More...
Read More...
Spray-dried, Biodegradable, Linezolid loaded Microspheres for Use in the Treatment of Lung Diseases
ABSTRACT
Introduction: Researchers worldwide are currently seeking innovative treatment options to combat the alarming increase in bacterial resistance to antimicrobial drugs. Staphylococcus aureus, a frequently encountered and potentially life-threatening bacterium, has become particularly…
Read More...
Read More...
Silica nanoparticles: A review of their safety and current strategies to overcome biological…
Abstract
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They have been used in many different biomedical fields including diagnosis, biosensing and drug delivery. Medical uses of SNP for anti-cancer, anti-microbial and theranostic applications are especially…
Read More...
Read More...
Controlled release mechanism of thymol loaded into mesoporous silica nanoparticles for active…
In order to overcome the poor water solubility and instability of thymol to enhance its bioavailability, mesoporous silica nanoparticles (MSNPs: SBA-15, SBA-16 and MCM-41) with different pore structures were developed using solution-gel method to carry and release thymol. The N2 …
Read More...
Read More...
Development and Optimization of a Novel Lozenge Containing a Metronidazole-Peppermint Oil-Tranexamic…
In-depth studies on essential oil–based nanoemulsions (NEs) have centered on a variety of oral health issues. NEs improve the delivery of nonpolar active agents to sites and thereby boost the dissolution and distribution of the agents. Metronidazole-peppermint oil-tranexamic acid…
Read More...
Read More...
Semi-solid extrusion 3D-printing of eucalypt extract-loaded polyethylene oxide gels intended for…
In pharmaceutics, 3D printing is considered as a promising future technology for fabricating more complex patient-specific drug delivery systems (DDSs). An anti-staphylococcal herbal preparation, “Chlorophyllipt”, is produced mainly in a liquid form by the pharmaceutical industry in Ukraine, and…
Read More...
Read More...
Lyophilized Lipid Liquid Crystalline Nanoparticles as an Antimicrobial Delivery System
Lipid liquid crystalline nanoparticles (LCNPs) are unique nanocarriers that efficiently deliver antimicrobials through biological barriers. Yet, their wide application as an antimicrobial delivery system is hindered by their poor stability in aqueous dispersions. The production of dried LCNP powder…
Read More...
Read More...
Cyclodextrin: A prospective nanocarrier for the delivery of antibacterial agents against bacteria…
Abstract
Supramolecular chemistry introduces us to the macrocyclic host cyclodextrin, which has a hydrophobic cavity. The hydrophobic cavity has a higher affinity for hydrophobic guest molecules and forms host-guest complexation with non-covalent interaction. Three significant cyclodextrin kinds…
Read More...
Read More...
Recent advances in chitosan-based materials; The synthesis, modifications and biomedical…
The attention to polymer-based biomaterials, for instance, chitosan and its derivatives, as well as the techniques for using them in numerous scientific domains, is continuously rising. Chitosan is a decomposable naturally occurring polymeric material that is mostly obtained from seafood waste.…
Read More...
Read More...
Electrospun composite nanofibers for treating infectious esophagitis
The electrospinning technique enables the convenient fabrication of non-woven fibrous materials with excellent properties such as fine diameters, a large surface area per unit mass, high porosity, high gas permeability, and small pore sizes. Nanofiber applications in healthcare systems continue to…
Read More...
Read More...