Capsules are a popular dosage form in the pharmaceutical industry because they provide an easy and convenient way to administer medications, offering precise dosage control. They can be formulated to contain a variety of active ingredients, including powders, liquids, and pellets, and can also be designed for immediate or extended release. Capsules protect sensitive drugs from environmental factors like light and air, enhancing drug stability and patient adherence.
Browsing Category
Capsules
Oxidative Stability in Lipid Formulations: a Review of the Mechanisms, Drivers, and Inhibitors of…
Abstract
The importance of lipid-based formulations in addressing solubility and ultimately the bioavailability issues of the emerging drug entities is undeniable. Yet, there is scarcity of literature on lipid excipient chemistry and performance, notably in relation to oxidative stability. While…
Read More...
Read More...
Hard gelatine capsules: DEM supported experimental study of particle arrangement effect on…
Hard gelatine capsules remain a relevant dosage form for today's pharmaceutical manufacturing. A wide range of colour and print options supports marketing, brand image and patient loyalty. However, the filling of these capsules with various modern dosage forms and combinations thereof may affect…
Read More...
Read More...
Does manual inspection still make sense?
Manual visual inspection is reliable in only 80% of cases. Such results have been reported by the FMEA (Failure Mode Effect Analysis) inspection process guidelines, taking into account multiple factors, such as time for observation, different viewing angles, different operator subjectivity, visual…
Read More...
Read More...
Aversion liquid-filled drug releasing capsule (3D-RECAL): A novel technology for the development of…
COVID19 has caused a significant socioeconomic burden worldwide. Opioid crisis was further intensified with the increasing number of opioid overdose/misuse related deaths in last two years. Abusers have adopted newer/efficient methods for manipulating and abusing commercial opioid formulations. Food…
Read More...
Read More...
Lonza Expands its Capsugel® Capsule Offering to Include Titanium Dioxide-Free White Hard Gelatin…
Basel, Switzerland, 09 May 2022 – Lonza has expanded its Capsugel® offering with a titanium dioxide-free (TiO2-free) white hard gelatin capsule, fulfilling the evolving demand of its customers to meet new titanium dioxide-free requirements for foods in the European Union.
This novel opacifying…
Read More...
Read More...
Spray-Drying of Hydroxypropyl β-Cyclodextrin Microcapsules for Co-Encapsulation of Resveratrol and…
The synergistic therapeutic benefits of resveratrol (RES) and piperine (PIP) have been proven for the treatment of various diseases. This study reports, for the first time, spray-drying of hydroxypropyl β-cyclodextrin (HP-β-CD) microcapsules for combined delivery of resveratrol and piperine. Phase…
Read More...
Read More...
The Development of Innovative Dosage Forms of the Fixed-Dose Combination of Active Pharmaceutical…
The development of innovative forms of combination drugs is closely related to the invention of the multilayer tablet press, polymers for pharmaceutical applications, the hot-melt extrusion process, and 3D printing in the pharmaceutical industry. However, combining multiple drugs within the same…
Read More...
Read More...
In Vitro and In Vivo Studies of a Verapamil-Containing Gastroretentive Solid Foam Capsule
Gastroretentive systems may overcome problems associated with incomplete drug absorption by localized release of the API in the stomach. Low-density drug delivery systems can float in the gastric content and improve the bioavailability of small molecules. The current publication presents…
Read More...
Read More...
Application of a novel electrostatic dry powder coating technology on capsules for enteric release
Dry coating of pharmaceutical dosages represents the future of functional coating given its environmental friendliness and cost effectiveness. Based on the electrostatic dry powder coating technology developed by our group, hard gelatin capsules and HPMC capsules were successfully coated for the…
Read More...
Read More...
Development and analysis of a novel loading technique for FDM 3D printed systems: Microwave-assisted…
In this paper, we describe a modular post-printing loading protocol for a 3D printed gastro-retentive drug delivery system. Fused Deposition Modelling (FDM) 3D printing was exploited for the rapid prototyping of a modular floating system (caps-in-cap). Optimized models were produced as blank PVA …
Read More...
Read More...