Capsules are a popular dosage form in the pharmaceutical industry because they provide an easy and convenient way to administer medications, offering precise dosage control. They can be formulated to contain a variety of active ingredients, including powders, liquids, and pellets, and can also be designed for immediate or extended release. Capsules protect sensitive drugs from environmental factors like light and air, enhancing drug stability and patient adherence.
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Capsules
Pharmacokinetic Properties of Acetyl Tributyl Citrate, a Pharmaceutical Excipient
Acetyl tributyl citrate (ATBC) is an (the Food and Drug Administration) FDA-approved substance for use as a pharmaceutical excipient. It is used in pharmaceutical coating of solid oral dosage forms such as coated tablets or capsules. However, the information of ATBC on its pharmacokinetics is…
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Pediatric Oral Formulations: An Updated Review of Commercially Available Pediatric Oral Formulations…
Oral pediatric formulations are either ready-to-use or require manipulation, and multi-use or single-use. Strong encouragement for preservative-free pediatric formulations has resulted in fewer multi-use solutions or suspensions in favor of single-use solid oral dosage forms. This updated review…
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Infacort®, Oral Hydrocortisone Granules with Taste Masking for the Treatment of Neonates and Infants…
05. March 2015
Background: Current treatment for adrenal insufficiency in neonates and infants is unsatisfactory as unlicensed adult formulations are used and the minimum unit dose available is a scored 5mg hydrocortisone tablet. These are difficult to administer to neonates and…
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3D printed devices in the gastrointestinal tract of rodents – imaging by PET/CT
04. December 2017
Abstract
Fused deposition modelling (FDM) 3D printing (3DP) is a revolutionary technology with the potential to transform drug product design in both the pre-clinical and clinical arena. The objective of this pilot study was to explore the intestinal behaviour…
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EXCIPIENT REQUIREMENTS IN THE FORMULATION OF SOLID ORAL DRUG FORMS
A Capsugel paper on the search for physiologically unobjectionable coloring agents for pharmaceutical drug formulations in capsules. Comparative analysis between the caplet and capsules wherecapsules are shown to shorten development times.
Excipient requirements in the formulation of solid oral…
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Development of a solid dosage platform for the oral delivery of bilayer vesicles
19. June 2017
Abstract
Within this work, we develop vesicles incorporating sub-unit antigens as solid dosage forms suitable for the oral delivery of vaccines. Using a combination of trehalose, dextran and mannitol, freeze-dried oral disintegrating tablets were formed which upon…
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Polymeric microcontainers improve oral bioavailability of furosemide
03. April 2016
Microcontainers with an inner diameter of 223 μm are fabricated using the polymer SU-8, and evaluated in vitro, in situ and in vivo for their application as an advanced oral drug delivery system for the poorly water soluble drug furosemide. An amorphous sodium…
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Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classification System…
31. March 2016
The objective was to assess the impact of larger than conventional amounts of 14 commonly used excipients on Biopharmaceutics Classification System (BCS) class 3 drug absorption in humans. Cimetidine and acyclovir were used as model class 3 drugs across three separate…
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Infacort®, Oral Hydrocortisone Granules with Taste Masking for the Treatment of Neonates and Infants…
29. March 2016
Background: Current treatment for adrenal insufficiency in neonates and infants is unsatisfactory as unlicensed adult formulations are used and the minimum unit dose available is a scored 5mg hydrocortisone tablet. These are difficult to administer to neonates and give…
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Formulation and evaluation of Thiocolchicoside Topical Gel by using different method
15. March 2016
Thiocolchicoside used for the effective treatment of muscle spasm, cramps, musculoskeletal and neuromuscular disorders. It is available in market in the form of capsules and injection. The major problem associated with thiocolchicoside is it's bioavailability which is…
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