Capsules are a popular dosage form in the pharmaceutical industry because they provide an easy and convenient way to administer medications, offering precise dosage control. They can be formulated to contain a variety of active ingredients, including powders, liquids, and pellets, and can also be designed for immediate or extended release. Capsules protect sensitive drugs from environmental factors like light and air, enhancing drug stability and patient adherence.
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Capsules
Comparison of Different Sorbitol Sorbitan Solutions as Gelatin Plasticizer
INTRODUCTION
Soft capsules are a popular dosage form for dispensing active pharmaceutical or nutraceutical materials. The shell material is frequently composed of gelatin, softened with considerable amount of plasticizer. They are especially adapted for liquids and for the formulation of hardly…
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Assessing the utility of in silico tools in early drug development: The case of a pharmaceutically…
Background: Depressive disorders contribute to an excruciating global mental health burden. Recently, there has been a great shift in interest towards substances with psychedelic potential as treatment for patients with resistant forms of depression, one of these substances being psilocybin. The…
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3D printed capsule shells for personalized dosing of cyclosporine-loaded SNEDDS
Abstract
Cyclosporine (CsA) is a potent immunosuppressant agent that has been used since 1980 for the treatment of various autoimmune diseases and is extensively used to enhance the survival rate of patients and grafts following organ transplant surgeries. CsA is a poorly soluble drug with a narrow…
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Quality by design aided self-nano emulsifying drug delivery systems development for the oral…
The primary objective of the research effort is to establish efficient solid self-nanoemulsifying drug delivery systems (S-SNEDDS) for benidipine (BD) through the systematic application of a quality-by-design (QbD)-based paradigm. Utilizing Labrafil M 2125 CS, Kolliphor EL, and Transcutol P, the…
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pH-dependent pressure-sensitive colonic capsules for the delivery of aqueous bacterial suspensions
Microbiome-based therapies hold great promise for treating various diseases, but the efficient delivery of live bacteria to the colon remains a challenge. Furthermore, current oral formulations, such as lyophilized bacterial capsules or tablets, are produced using processes that can decrease…
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Manufacturing classification system for oral solid dosage forms of traditional Chinese medicines(Ⅰ):…
Oral solid dosage (OSD) occupies a key position in the market of Chinese patent medicines and new traditional Chinese medicines. Processing route is the foundation for the research and development of traditional Chinese medicine OSDs. On the basis of prescriptions and preparation methods of 1 308…
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Dispensing Oral Temozolomide in Children: Precision and Stability of a Novel and Ready to Use Liquid…
Abstract
Temozolomide (TMZ) is part of the therapeutic armamentarium used in managing pediatric cancers; however, available oral forms (capsules) are not adapted for use in children. Our aim was to assess the dose accuracy and stability of TMZ using capsule contents mixed with food compared with a…
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Retrospective analysis of the biopharmaceutics characteristics of solid oral Modified-Release drug…
Abstract
Background
Modified Release (MR) orally administered drugs products differ from Immediate-Release (IR) drug products in their drug release site and/or rate to offer therapeutic advantages. It is important to understand the biopharmaceutics factors that determine how a drug works in the…
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LomaFlow – Improved Flowability with Mineral-Based Anti-Caking Agents
Dr Paul Lohmann´s mineral-based portfolio of anti-caking agents is set to simultaneously enhance flowability and provide strong anti-caking properties. The LomaFlow product range includes Magnesium and Calcium Salts. These meticulously crafted solutions are designed to (re)formulate a wide spectrum…
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Evidence of Reliable Gastro-Resistance of Novel Enteric Ready-to-Fill Capsules Simplifying…
Developing delayed-release formulations for acid-sensitive actives can be a costly and time-consuming process. However, ready-to-fill functional capsules, such as EUDRACAP® can significantly mitigate these challenges. The in vitro performance of EUDRACAP® enteric was evaluated in two typical…
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