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Co-processed excipients
Co-processed Excipient for Direct Compression Designed for Orally Disintegrating Tablets
Developing orally disintegrating tablets (ODTs) is a worldwide trend. In recent years, new excipients and excipient blends have enabled manufacturers to produce ODTs using conventional equipment, i.e., blenders and tablet presses. One such product is GRANFILLER-D, a co-processed excipient for direct…
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Preparation of Bilayer ODTs with Superior Interfacial Strength Using GRANFILLER-D
In recent years, multilayer tablets have drawn attention as dosage form that enable the production of combination drugs with API stability and precisely controlled dissolution rates, and many studies on such tablets have been reported. However, there are still few reports on the application of…
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Characterization and comparison of deferasirox fast disintegrating tablets prepared by direct…
The aim of this study was to develop direct compressed and lyophilized fast disintegrating/dissolving tablets (FDTs) that enhanced disintegration and dissolution of deferasirox, a drug with poor solubility and bioavailability. Although there are conventional oral tablets and tablets for oral…
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Oral tablet formulations containing cyclodextrin complexes of poorly water soluble cefdinir to…
Cefdinir (CFD) is an oral cephalosporin antibiotic commonly used in the treatment of community-acquired infections. The oral bioavailability of CFD is limited due to its poor aqueous solubility. Cyclodextrins (CyDs) and their chemically modified derivatives are used in the pharmaceutical field to…
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Benefits of Co-processed High-Functionality Excipients in a Continuous Direct Compression Process…
Continuous manufacturing offers significant advantages over conventional batch processing such as smaller equipment, less footprint and no need for upscaling experiments. With these benefits, come challenges as well. In a fully continuous process, the excipients must be added through individual…
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How to register co-processed excipients – MEGGLE Excipients & Technology
Co-processed Excipients:
Drug approval process | Compendial vs. Novel Excipients
Common Technical Documentation Format – CTD
Throughout a drug approval process a team of drug regulatory experts needs to compile mandatory documentation, which comply with the common technical documentation format.…
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Co-processed excipients for direct compression of tablets
Tablets are the most frequently employed dosage form. Their advantage lies in their availability, easy administration, good stability, and low price. The easiest technology to produce tablets is direct compression, even though the use of the method requires overcoming many obstacles, mainly related…
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Formulation and Evaluation of Fast Dissolving Tablet of Montelukast by using Co-processed Excipients
The current research work was aimed with an objective of formulation development of fast dissolving tablet of montelukast by using co-processed excipient and to evaluate the effect of co-processed excipient over physical mixture of same excipients.
The co-processed excipients were developed by…
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Development and Evaluation of Controlled and Simultaneous Release of Compound Danshen Based on a…
In the study, we developed a novel oral dosage form of Compound Danshen to resolve the problems of low bioavailability, disequilibrium in drug release, and stomach degradation of active components of Compound Danshen in conventional formulas.
A colon-specific osmotic pump capsule (COPC) of…
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Review on novel pharmaceutical co-processed excipients
Excipients play an important role in formulating a dosage form. In recent years drug formulation scientists have recognized that single component excipients do not always provide the requisite performance to allow certain active pharmaceutical ingredients to be formulated or manufacturing…
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