Pharma Excipients
Coating Systems and Additives
Titanium dioxide free coatings – Biogrund information
For decades, titanium dioxide (TiO2) has been used as a white pigment due to its very high opacity and brightness. Therefore, it has a wide range of applications, from being a colouring ingredient of pharmaceutical film coating, to food application colouring.
On the basis of current…
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Current Developments in Excipient Science – Implication of Quantitative Selection of Each…
Implication of Quantitative Selection of Each Excipient in Product Development
Excipients’ role in designing different dosage forms does not require any introduction. These are the additives that are added to the formulation along with pharmacologically active substance. The main purpose of adding…
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Design, formulation and manufacture of film-coated drug products
Film coating is a common step in tablet manufacture that can be used to improve product appearance, organoleptic properties, or to facilitate swallowing. Functional film coats can also be used as a part of the product’s stabilisation strategy and to modify or delay drug release.
The film coat,…
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What are pharmaceutical film coatings? Part 1 -Tablets
There a many reasons for coating of different pharmaceutical products such as pellets, granules, capsules, powders and crystals. In this article, we will concentrate on the film-coating of tablets.
The procedure of coating tablets is a complex process that results in the forming of a thin layer…
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Gellan gum and polyvinylpyrrolidone (PVP) as binding agents in extrusion/spheronization pellet…
The aim of this work was to evaluate gellan gum as binder in pellet formulations, with theophylline as the model drug, in comparison with polyvinylpyrrolidone (PVP). A full 32 factorial design was realized, with binder and dilu- ent factors at three levels each. Pellets were produced by the…
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A combination of the advantages of film coating and sugar coating?
Sugar Coating – from conventional to continuously automated When it comes to aesthetics, shine and good insulation, traditional sugar-coated tablets are still a very popular dosage form. Among the numerous coating layers, the bad-tasting and smelling active ingredient is sufficiently masked and…
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An introduction to pharmaceutical film coatings
A wide variety of pharmaceutical products, including pellets, granules, capsules, powders, and crystals are often film coated. In this present article, we will concentrate on the film-coating of tablets.
The procedure of coating tablets is a complex process that results in the forming of a thin…
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High shear blending with glyceryl distearate provides individually coated drug particles for…
Lipid coating in a high shear blender without heating and complex spray mechanism was investigated as a simplified approach to hot melt coating in a fluid bed device. Potassium chloride was coated with 20% glyceryl distearate using both processes. Microscopic images revealed that the drug surface…
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Designing pH-Responsive Biodegradable Polymer Coatings for Controlled Drug Release via Vapor-Based…
We present the design of a novel pH-responsive drug release system that is achieved by solventless encapsulation of drugs within a microporous membrane using a thin capping layer of biodegradable polymethacrylic anhydride (PMAH) coating. The coating was synthesized via a mild vapor polymerization…
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Optical coherence tomography as a novel tool for in-line monitoring of a pharmaceutical film-coating…
Optical coherence tomography (OCT) is a contact-free non-destructive high-resolution imaging technique based on low-coherence interferometry. This study investigates the application of spectral-domain OCT as an in-line quality control tool for monitoring pharmaceutical film-coated tablets. OCT…
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