A wide variety of pharmaceutical products, including pellets, granules, capsules, powders, and crystals are often coated. The procedure of coating tablets is a complex process that results in the forming of a thin layer around the tablet. This layer is in the range of 20 to 200 μm in thickness, or around 1 to 9% of the initial weight of the tablet.
Pharma Excipients
Coating
Methocel™ Cellulose Ethers – A product that can do it all
THE POSSIBILITIES ARE ENDLESS
Pharmaceutical companies are continuously looking for ways to innovate – through new technologies such as controlled release systems and oral films, or through faster and more efficient manufacturing processes. Did you know that just one product can help do all of…
Read More...
Read More...
HPMCP – Cellulose derivative for enteric coating by Shin-Etsu
Since the introduction of HPMCP (hypromellose phthalate USP/NF, JP, EP) in 1971, it has proved its value in enteric coating using organic solvent. The chemical structure of HPMCP is a monophthalic acid ester of hypromellose.The threshold pH value for rapid disintegration of HPMCP can be controlled…
Read More...
Read More...
Application of Liquisolid Pellets Technology for Improving Dissolution of Posaconazole: A DoE Based…
Abstract
Purpose
Posaconazole (PSZ) is BCS class-II drug that displays variable bioavailability upon oral administration due to extremely low and pH-dependent solubility.
Method
The present investigation was aimed to formulate and evaluate liquisolid pellets of PSZ for improving its…
Read More...
Read More...
PHARMACOAT® – Easy to use film coating material that provides an excellent finish
Shin-Etsu Chemical supplies the various excipients for pharmaceutical industry and developed PHARMACOAT® in the 1960s during the early days of film coating and since then it has been the subject of a continuous development and quality improvement.
The PHARMACOAT® grades are low viscous…
Read More...
Read More...
Impact of two-step glidant mixing process on flow performance of coated curcumin – in vitro,…
Curcumin is a well-known phenolic compound obtained from Curcuma Longa L. It is used popularly as an antioxidant, anti-inflammatory, antispasmodic, antithrombotic, anticancer as well as immune-modulator. In the last couple of years, few studies showed the usefulness of curcumin against Helicobacter…
Read More...
Read More...
Taste-Masked Pellets of Warfarin Sodium: Formulation towards the Dose Personalisation
Abstract
The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim of this feasibility study was to formulate the taste-masked warfarin-containing pellets to be applicable for dose personalisation and to improve patient compliance, as well as…
Read More...
Read More...
Shin-Etsu AQOAT® – Enteric coating polymer and solid dispersion carrier
Shin-Etsu supplies the various excipients for pharmaceutical industry. Let us introduce you Shin-Etsu AQOAT® Hypromellose acetate succinate (HPMCAS, NF, JP), an enteric coating material that can be used in aqueous or organic media.
Hypromellose is a non-toxic material which has been used in…
Read More...
Read More...
Colon Drug Delivery Systems Based on Swellable and Microbially Degradable High-Methoxyl Pectin:…
Abstract
Oral colon delivery systems based on a dual targeting strategy, harnessing time- and microbiota-dependent release mechanisms, were designed in the form of a drug-containing core, a swellable/biodegradable polysaccharide inner layer and a gastroresistant outer film. High-methoxyl pectin was…
Read More...
Read More...
Effects of omitting titanium dioxide from the film coating of a pharmaceutical tablet
An industrial case study of attempting to comply with EU regulation 2022/63
Recently, concerns have been raised about the safety of titanium dioxide (TiO2), a commonly used component of pharmaceutical film coatings. The European Union has recently prohibited the application of this material in the…
Read More...
Read More...
Exploring Immersion Coating as a Cost-Effective Method for Small-Scale Production of Enteric-Coated…
Abstract
The coating process for solid dosage forms is widely used in the pharmaceutical industry but presents challenges for small-scale production, needed in personalized medicine and clinical or galenic settings. This study aimed to evaluate immersion coating, a cost-effective small-scale…
Read More...
Read More...