A wide variety of pharmaceutical products, including pellets, granules, capsules, powders, and crystals are often coated. The procedure of coating tablets is a complex process that results in the forming of a thin layer around the tablet. This layer is in the range of 20 to 200 μm in thickness, or around 1 to 9% of the initial weight of the tablet.
Pharma Excipients
Coating
Changes in Tablet Color Due to Light Irradiation: Photodegradation of the Coating Polymer,…
The color of the tablets and capsules produced by pharmaceutical companies is important from the perspectives of product branding and counterfeiting. According to some studies, light can change tablet color during storage. In this study, tablets comprising amlodipine besylate (AB), a well-known…
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Chitosan film of thiolated TPGS-modified Au-Ag nanoparticles for combating multidrug-resistant…
The widely used vitamin-E based amphiphilic material, tocopheryl polyethylene glycol succinate (TPGS) is further improvised as redox-sensitive thiolated TPGS (TPGS-SH), which has been developed by attaching 4-aminothiophenol. Further, TPGS and TPGS-SH-coated bimetallic gold-silver nanoparticles…
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Extending the Use of Optical Coherence Tomography to Scattering Coatings Containing Pigments
Coating thickness is a critical quality attribute of many coated tablets. Functional coatings ensure correct drug release kinetics or protection from light, while non-functional coatings are generally applied for cosmetic reasons. Traditionally, coating thickness is assessed indirectly via offline…
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A Novel Combined Dry Powder Inhaler Comprising Nanosized Ketoprofen-Embedded Mannitol-Coated…
Pulmonary inflammations such as chronic obstructive pulmonary disease and cystic fibrosis are widespread and can be fatal, especially when they are characterized by abnormal mucus accumulation. Inhaled corticosteroids are commonly used for lung inflammations despite their considerable side effects.…
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A dual catalytic functionalized hollow mesoporous silica-based nanocarrier coated with…
Abstract
In this study, we introduced a multifunctional hollow mesoporous silica-based nanocarrier (HMSN) for the targeted delivery of irinotecan (IRT) to colorectal cancer cells. Due to their large reservoirs, hollow mesoporous silica nanoparticles are suitable platforms for loading significant…
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Controlling the drug release with functional film coating
Functional film coatings are a topic which considers many formulators. Therefore we gladly share this interesting overview by BIOGRUND.
Definition of “Functional Film Coating”:
A functional film coating has an influence on the drug release and is used to modify the release of the active…
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Improving Inhalation Performance with Particle Agglomeration via Combining Mechanical Dry Coating…
Agglomerate formulations for dry powder inhalation (DPI) formed with fine particles are versatile means for the highly efficient delivery of budesonide. However, uncontrolled agglomeration induces high deposition in the upper airway, causing local side effects due to high mechanical strength, worse…
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Flexible Coatings Facilitate pH-Targeted Drug Release via Self-Unfolding Foils: Applications for…
Ingestible self-configurable proximity-enabling devices have been developed as a non-invasive platform to improve the bioavailability of drug compounds via swellable or self-unfolding devices. Self-unfolding foils support unidirectional drug release in close proximity to the intestinal epithelium,…
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Development of a New Jelly Coating Technology (Oral Jelly Coating) to Improve Prescribed Medication…
Oral drug delivery is currently the gold standard in the pharmaceutical industry, regarded as the safest, most convenient and most economical method of drug delivery with the highest patient compliance . Among oral formulations, tablets and capsules are the most preferred dosage forms, but there are…
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ApoE – functionalization of nanoparticles for targeted brain delivery – a feasible…
Abstract
The blood–brain barrier (BBB) poses a major obstacle in the treatment of all types of central nervous system (CNS) diseases. Small interfering RNA (siRNA) offers in principle a promising therapeutic approach by downregulating disease-related genes via RNA interference. However, the BBB is…
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