Continuous manufacturing

Abstract Continuous manufacturing is gaining increasing interest in the pharmaceutical industry, also requiring real-time and non-destructive quality monitoring. Multiple studies have already addressed the possibility of surrogate in vitro dissolution testing, but the utilization has rarely been…
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Abstract After decades of development, hot melt extrusion (HME) technology has matured as a well-established pharmaceutical methodology. Through the process of extruding both drug and carrier materials in a molten state under specific conditions of pressure, velocity, and screw design, this…
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MEDELPHARM is passionate about designing and manufacturing easy-to-use, fast, reliable equipment for R&D specialists. For formulation scientists looking for assistance in powder characterization, solid dosage formulation or production troubleshooting, MEDELPHARM offers a comprehensive…
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This poster was presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical  (PBP) Technology, 18 - 21 March 2024, Vienna, Austria: INTRODUCTION Hot melt extrusion (HME) has become increasingly popular in pharmaceutical manufacturing over the last decade1. This…
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MEDELPHARM is passionate about designing and manufacturing easy-to-use, fast, reliable equipment for R&D specialists. For formulation scientists looking for assistance in powder characterization, solid dosage formulation or production troubleshooting, MEDELPHARM offers a comprehensive…
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Presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical  (PBP) Technology, 18 - 21 March 2024, Vienna, Austria: INTRODUCTION The predominant approach for manufacturing nanocarriers on an industrial scale is batch production . Here, a specific quantity of raw…
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Presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical  (PBP) Technology, 18 - 21 March 2024, Vienna, Austria: Introduction A Process Analytical Technology (PAT) strategy for process and product monitoring is important to ensure adequate product quality. This is…
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THE NEW STYL’ONE NANO is a revolutionary benchtop R&D press for demanding formulation and scientists with price performance in mind. Instruments for every formulation scientist with price performance in mind POWDER COMPACTION SCIENCE CONCENTRATED IN A BENCHTOP R&D PRESS Tableting has…
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Abstract In this study, an in-depth comparison was made between batch and continuous direct compression using similar compression set-ups. The overall material processability and final tablet quality were compared and evaluated. Correlations between material properties, process parameters and…
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STYL’ONE EVO TABLETING INSTRUMENT The all-in-one multi-functional R&D press from early API characterization and formulation to scale-up at production speed The most advanced R&D press designed as multifunction tool adapted to every demanding need from early research to production support…
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