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Copovidone
Effect of the molecular mobility of water adsorbed by disintegrants on storage-induced hydrolytic…
The purpose of this study was to investigate the effect of molecular mobility of water adsorbed by disintegrants on the hydrolytic degradation of active pharmaceutical ingredients (APIs). Fourteen different disintegrants were tested. First, powdered disintegrants were stored at conditions of 40…
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Compaction and tableting properties of composite particles of microcrystalline cellulose and…
Excipients with improved functionality have continued to be developed by the particle engineering strategy of co-processing. The aim of this study was to evaluate the compaction and tableting properties of composite particles of microcrystalline cellulose (MCC) and crospovidone (CPV) engineered by…
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In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations
The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. In some cases the drug is barely soluble; in others, the rapid transit of the formulation through the gastrointestinal tract (GIT) makes it dicult to achieve therapeutic levels…
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Cushioning Pellets based on Microcrystalline Cellulose – Crospovidone Blends for MUPS Tableting
Compaction of multiple-unit pellet system (MUPS) tablets has been extensively reported to be potentially challenging. Thus, there is a need for non-segregating cushioning agents to mitigate the deleterious effect of the compaction forces. This study was designed to investigate the use of porous…
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Kollidon® The original PVP for solid oral dosage forms – overview
Kollidon is the original povidone for solid dosage forms. In this summary page you find the overview on the different types and information on the products including different manufacturing locations and product brochure.
The innovative innovative PeroXealTM packaging concept to limit peroxide…
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Amorphous Solid Dispersions in Early Stage of Formulation Development: Predicting Excipient…
Excipients play an important role in the formulation of dosage forms and can be used to improve the bioavailability of a drug through physical interactions that alter the rate of dissolution of a drug. The objective of this study was to predict the effect of formulation on the dissolution rate of a…
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Ashland announces global price increase for vinyl pyrrolidone- and cellulosic-based pharmaceutical…
Ashland announces global price increase for vinyl pyrrolidone- and cellulosic-based pharmaceutical excipient products
WILMINGTON, Del. - Ashland Specialty Ingredients, a commercial unit of Ashland Inc. (NYSE: ASH), is increasing the price of its portfolio of Aqualon™ ethylcellulose and sodium…
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