Pharma Excipients
DC excipient
Kollitab™ DC 87 L – BASF’s premium coprocessed excipient
BASF’s premium coprocessed excipient is optimized for your direct compression processes.
Our scientists carefully designed this best-in-class product to maximize flowability and tablet strength, with a formulation that has high stability and low sensitivity to overblending. Its round particle shape…
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Taking Vitamin D Supplements to the Next Level with galenIQ™
Although previously seen as a “winter time” supplement when shorter days mean that exposure to natural sunlight is limited, vitamin D is rapidly becoming a year-round topic for many people as consumers are increasingly aware of its role in supporting the immune system. Able to activate the innate…
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Process Model Approach to Predict Tablet Weight Variability for Direct Compression Formulations at…
Optimizing processing conditions to achieve a critical quality attribute (CQA) is an integral part of pharmaceutical quality by design (QbD). It identifies combinations of material and processing parameters ensuring that processing conditions achieve a targeted CQA. Optimum processing conditions are…
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Tailoring Rational Manufacturing of Extemporaneous Compounding Oral Dosage Formulations with a Low…
Low amounts of minoxidil in oral dosage forms are commonly prescribed as anti-alopecic pharmacological treatments. Side effects are usually related to individual susceptibility. However, poor drug content and mass uniformity can lead to a potential risk of overdosing, and higher chances to…
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HiSORAD™ – Solving content uniformity issues in ODT prepared by direct compression
Introduction
Direct compression is the simplest tableting method, contributing to both energy savings and cost advantages. However, maintaining content uniformity of active pharmaceutical ingredient (API) in tablets prepared by direct compression can be challenging, as powders with different…
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Pulsatile Delivery System for Antihypertensive Drug
The purpose of present work was to formulate an oral pulsatile drug delivery system to achieve time release of felodipine, based on chronopharmaceutical approach for the treatment of hypertension. System was prepared in the form of two layered tablets by press coating method. Active rapid release…
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Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis…
Epidermolysis bullosa is a genetically heterogenous skin fragility disorder with multiorgan involvement appearing already in newborn children. Severe progressive fibrosis follows skin blistering, mucosa lesions, and wound healing, favouring development of highly aggressive squamous cell carcinomas.…
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Bilayer Buccal Tablets of Furosemide: Design and Evaluation
Aim: In the present study, mucoadhesive bilayer buccal tablets of furosemide were fabricated with the objective of avoiding first-pass metabolism and enhancing the bioavailability along with reducing the dosing frequency.
Methodology: Direct compression method was used to prepare bilayer buccal…
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System model driven selection of robust tablet manufacturing processes based on drug loading and…
Mechanistic process modeling presents an opportunity to reduce experimental burden, enabling relationships between process parameters and product attributes to be mapped out using in-silico experiments. A system model of a pharmaceutical tablet manufacturing process comparing dry granulation with…
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Solid Dispersion of Artemether in Fast Disintegrating Tablet to Enhance Dissolution Rate and Oral…
Objectives: Artemether (ART), an antimalarial drug, have poor solubility and low bioavailability. Therefore, solid dispersion of the drug was formulated using Soluplus (SOL) and was incorporated in the fast disintegrating tablet.
Materials and Methods: The solid dispersion (SD) was prepared using…
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