Pharma Excipients
DC excipient
Formulation and Development of Flurbiprofen Colon-Specific Eudragit Coated Matrix Tablets: Use of a…
The rationale for the current investigation is to study the crude banana peel (CBP) powder efficiency as a novel natural time-dependent polymer along with a pH-sensitive polymer to develop flurbiprofen colon-specific tablets. The direct compression method is utilized to prepare the flurbiprofen-CBP…
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Investigating the Impact of Co-processed Excipients on the Formulation of Bromhexine Hydrochloride…
Abstract
Purpose
Orodispersible tablets (orally disintegrating tablets, ODTs) have been used in pharmacotherapy for over 20 years since they overcome the problems with swallowing solid dosage forms. The successful formula manufactured by direct compression shall ensure acceptable mechanical…
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Leveraging a multivariate approach towards enhanced development of direct compression extended…
Extended release formulations play a crucial role in the pharmaceutical industry by maintaining steady plasma levels, reducing side effects, and improving therapeutic efficiency and compliance. One commonly used method to develop extended release formulations is direct compression, which offers…
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Design, Characterization and Evaluation of Quick Dissolving Matrix BARETab® ODT Tablet In…
Abstract
The oral dissolving tablets is defined as one, which has drug in it and when placed on tongue dissolves completely within a limited span of time, without additional requirement of water. Drug is released, dispersed in the saliva and swallowed and subsequently absorbed in the…
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50 Shades of White – Lactose in Direct Compression
Introduction
Looking at an excipient suppliers Lactose portfolio, the variety might be overwhelming. There are many different Lactose types, some are unmodified crystals of Lactose Monohydrate und differ mainly in particle size but others have been modified in their habitus by spray drying or wet…
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Study of Powder and Tableting Functionality Towards Evaluation and Characterisation of BARETab® PH…
Abstract
BARETab® PH is a multi-functional ready to use premixed, co-processed ingredient for direct compression (DC) formulations. It is a combination of selective, largely used excipients for DC. Direct compression is the most widely used tableting method because of the simple manufacturing…
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Comparison of properties on Orally Disintegrating Tablets (ODTs) produced by direct compression or…
Abstract
Orally disintegrating tablets (ODTs) is a popular drug delivery system as they dissolve in the mouth, usually within seconds which enables easy medication for patients with problem swallowing. In this thesis properties of ODTs were compared when produced with direct compression of the…
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A technical note: Characterization and evaluation of novel, ready to use coprocessed excipient in…
Abstract
A tablet is composed of different excipients and drug. All excipients have different properties with applications. Excipients are used to provide bulk and help to bind API into a dosage form, excipient should be inert in nature with respectable physical properties. Because the physical…
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Drying capacity of a continuous vibrated fluid bed dryer – Statistical and mechanistic model…
The drying capacity of a continuous vibrated fluid bed dryer was studied using a DoE by varying microcrystalline cellulose content in the formulation, water amount in the twin-screw granulation, inlet air temperature, air flow rate and the acceleration of the horizontal fluid-bed. Temperature and…
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Effects of Granulated Lactose Characteristics and Lubricant Blending Conditions on Tablet Physical…
Abstract
Lactose is an excipient used extensively for bulking, diluting, and molding active pharmaceutical ingredients in tablet manufacturing. Particularly, granulated lactose (GL) intended for direct powder compression has distinct properties due to differences in manufacturing methods. It…
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