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Diabetes
The effects of the treatment conditions on the dissolution profile of ethylcellulose coated pellets
Due to the additional particle coalescence in the coating, changes in the dissolution profile occur over time in the formulations coated by aqueous ethylcellulose latex. Dry thermal treatment (DT) of the coating can be used as a prevention of this process. Alternatively, it is advisable to take…
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Oral delivery of insulin via mesoporous carbon nanoparticles
In this article, a new type of mesoporous carbon nanoparticles (MCN) was fabricated as a potential oral delivery system of insulin to reduce the adverse reactions by hypodermic injection. The mesoporous carbon nanoparticles-carried insulin (MCNI) was studied using scanning electron microscopy (SEM),…
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Integration of 3D printing with dosage forms: A new perspective for modern healthcare
13. August 2018
3D printing is an additive manufacturing technique capable of producing various 3D drug products, medical devices, tissues and organs from digital designs. The first FDA approved 3D drug product, Spritam®, has encouraged and attracted many researchers in…
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Dosing challenges in respiratory therapies
07. July 2018
The pulmonary route of administration has been commonly used for local lung conditions such as asthma and chronic obstructive pulmonary disease (COPD). Recently, with the advent of new technologies available for both formulation and device design,…
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A review on pH and temperature responsive gels and other less explored drug delivery systems
02. June 2018
Any imbalance in body's pH or temperature may alter immune response and lead to conditions such as autoimmune disorders, infectious diseases, cancer and diabetes. Dual pH and thermo-responsive carriers have been striving forward as next generation…
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Drug patent expirations of 2018
04. April 2018
Drug patent expirations of 2018 - The Top 15
Article from Fierce Pharma by Eric Sagonowsky - April 3, 2018
Each year, dozens of branded pharmaceutical products lose their patent protections in a process that routinely paves the way for cheap generics. This…
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2017 saw record approvals of generic drugs, novel drugs and devices by the USFDA
04. January 2018
The year gone by saw the highest number of generic drug approvals by the US Food and Drug Administration (FDA), along with the most ever novel drugs (46); the most ever novel devices, and the first ever gene therapies.
In 2017, 46 new…
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Dry powder inhaler for pulmonary drug delivery
17. October 2017
Pulmonary drug delivery is the promising delivery route to treat not only respiratory diseases but also systemic diseases and has proven as a potential delivery route for complex drugs that cannot be delivered orally. Development of dry powder inhalation…
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Biodegradable Nanoparticles for Delivering Drugs
26. September 2017
ABSTRACT- Dialysis is the only mode of available palliative therapeutic modality to patient with end stage of renal disease. Diabetes is one of the foremost common causes of chronic renal disease and affecting large number of diabetic patients. By many…
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Microspheres of insulin-Eudragit complex: Formulation, characterization and in vivo studies
14. August 2017
Insulin, a hormonal drug for the management of diabetes mellitus has continued to attract attention of many researchers and pharmaceutical formulators for more than a decade. However, its low oral bioavailability due to the activities of intestinal…
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