Browsing Category
Diabetes
Calcium alginate microspheres containing metformin hydrochloride niosomes and chitosomes aimed for…
07. August 2017
Abstract
Metformin is an oral hypoglycemic agent used in the type 2 diabetes, whose poor bioavailability and short half-life make the development of effective extended-release formulations highly desirable. Different metformin-loaded chitosomal and…
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Can natural polymers assist in delivering insulin orally?
31. May 2017
Abstract
Diabetes mellitus is one of the most grave and lethal non communicable diseases. Insulin is normally used to medicate diabetes. Due to bioavailability issues, the most regular route of administration is through injection, which may pose…
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Melatonin: A Silent Regulator of the Glucose Homeostasis
20. April 2017
Melatonin: A Silent Regulator of the Glucose Homeostasis
Abstract
In the human organism, the circadian regulation of carbohydrates metabolism is essential for the glucose homeostasis and energy balance. Unbalances in glucose and insulin tissue and blood…
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Preparation and investigation of controlled-release glipizide novel oral device with…
11. April 2017
Abstract
The purpose of this study was to explore the feasibility of combining fused deposition modeling (FDM) 3D printing technology with hot melt extrusion (HME) to fabricate a novel controlled-release drug delivery device. Glipizide used in the…
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Formulation of hydrophobic peptides for skin delivery via coated microneedles
16. March 2017
Abstract
Microneedles (MNs) have been investigated as a minimally-invasive delivery technology for a range of active pharmaceutical ingredients (APIs). Various formulations and methods for coating the surface of MNs with therapeutics have been proposed…
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An Innovative Smart Oral Delivery Technology for Proteins and Peptides
22. July 2016
Andrea Engel, PhD, Head of Particle Formulation Laboratory; Anne Benedikt, PhD, Head of Biopharmaceutical Laboratory; and Hans Baer, MSc, Senior Project Manager, all of Evonik, explain how their recently introduced new modular platform technology for improving the oral…
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