Disintegrants and superdisintegrant excipients are essential components used in the pharmaceutical industry to enhance the dissolution and bioavailability of active pharmaceutical ingredients (APIs). These excipients facilitate the disintegration and rapid breakup of tablets or capsules, which ultimately increases their rate of absorption in the body.
Pharma Excipients
Disintegrant / Superdisintergrant
New all-in-one tableting solution with filler, binder, disintegrant and lubricant: Kollitab™ DC 87 L
How can Kollitab™ DC 87 L help you?
Superior flowability
High tablet strength at broad compression forces
Fast disintegration
Order Kollitab™ DC 87 L here!
Key benefits
Manufacturing
Enables fast tablet development
Simplifies formulation development
Reduces…
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The evaluation of the effect of different superdisintegrants on the drug release from FDM 3D printed…
Paracetamol-loaded tablets were printed by fused deposition modelling technique, using polyvinyl alcohol as a backbone polymer and Affinisol™ HPMC as a plasticizer in all formulations. Four different strategies were applied in order to accelerate the drug release from the tablets. First, different…
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Pharmatrans excipients for improved compactibility and flowability in tablet manufacture
Pharmatrans SANAQ AG specializes in pharmaceutical excipients and active ingredients, harnessing a spirit of innovation and commitment to high quality products based on a solid platform of experience established over almost four decades.
The Pharmatrans SANAQ product portfolio includes a range of…
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Formulation and Evaluation of Baclofen-Meloxicam Orally Disintegrating Tablets (ODTs) Using…
Purpose: This study aimed to formulate an orally disintegrating tablet (ODT) containing both baclofen and meloxicam together for treating osteoarthritis.
Methods: Direct compression method was used to prepare ODTs using three types of co-processed excipients (Prosolv ODT G2®, F-melt®, and…
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Downstream processing of spray-dried ASD with hypromellose acetate succinate – Roller compaction and…
Despite wide commercial application of hypromellose acetate succinate (HPMCAS) in spray-dried amorphous solid dispersion (ASD) drug products, little information is available in the references on downstream processing of spray-dried dispersions with HPMCAS. Poor flow and high dilution factor are a…
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Oil adsorption – The Interview with Fuji Chemical
Fuji Chemical Industries specializes in producing porous spray-dried excipients for the pharmaceutical and nutraceutical markets. They spray-dry their excipients to produce free-flowing granules and unique internal structures that enhance compressibility and functionality. These structures are ideal…
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Statistical design of experiment-based formulation development and optimization of 3D printed oral…
Purpose
Producing several controlled- release 3D printed tablets from polymer blends with the required target product profile has been a challenge. Thus, experimental design could be applied to rationally explore the impact of the formulation excipients on drug release.
Methods
The optimization…
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See the overview of Parteck® Functional Excipients
When you design a solid dosage form, there are many factors to consider: the active ingredient, bioavailability enhancement, release kinetics, specific dosage, packaging, shelf life, and more.
Our Parteck® excipients were designed with the formulator’s challenges in mind and are particle…
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Design and Development of Taste Masked Formulations of Model Drug by Using Eudragit L-100: A Recent…
Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor medication with a very bitter taste that plays an essential role in patient compliance in the oral dosing form. In this study, an attempt was made to mask the bitter taste of Tenofovir Disproxil Fumarate utilising a…
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Time-controlled release by the incorporation of superdisintegrants within the coat of zein dry…
The aim of this work was to develop zein-based press coated tablets for delayed, time-controlled drug release. Press coated tablets containing dextrates and chlorpheniramine maleate (BCS class 1 drug) in the core, and zein and either NaCl, sodium starch glycolate (SSG) or crospovidone (XPVP) in the…
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