Drug Carrier excipients enhance and interact with the properties of active pharmaceutical ingredients (APIs).
Pharma Excipients
Drug Carrier
The Expanded Role of Chitosan in Localized Antimicrobial Therapy
Chitosan is one of the most studied natural origin polymers for biomedical applications. This review focuses on the potential of chitosan in localized antimicrobial therapy to address the challenges of current rising antimicrobial resistance. Due to its mucoadhesiveness, chitosan offers the…
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Omyanutra® 300 DC – Direct compressible, porous excipient for nutraceuticals
Producing nutraceuticals in solid dosage form is complex and faces many challenges. In production, manufacturers choose either wet or dry granulation, or, which is becoming more popular, direct compression. Direct compression (DC) results in the shortest, most efficient and least complex way to…
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The Influence of Relative Humidity and Storage Conditions on the Physico-chemical Properties of…
Dry powder inhalers (DPIs) are favorable devices for the delivery of dry formulations to the lungs; still, they largely fail to deliver higher doses of active pharmaceutical ingredient (API) to the lower airways. Addition of fine particles of excipient (fines) to the blend of API and carrier was…
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Approaches of 3D printing in current drug delivery
Three-dimensional printing (3DP) is predicted to be one of the most progressive innovations within the pharmacy. Nowadays, the use of 3D printing technologies in drug delivery systems has exponentially expanded, due to its potential advantages over customizing drugs in individually adjusted doses.…
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Nanocrystal-based 3D-printed tablets: Semi-solid extrusion using Melting solidification printing…
This is the first report on the inclusion of nanocrystals (NCs) within 3D-printed oral solid dosage forms – 3D-printed tablets or printlets – produced by the Melting Solidification Printing Process (MESO-PP) 3D printing technique. This method allowed the incorporation of albendazole (ABZ)…
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Characterization of excipients to improve pharmaceutical properties of sirolimus in the…
Enhanced drug release and bioavailability of poorly soluble active pharmaceutical ingredient (API) can be achieved via a fluidized bed coating integrated with supercritical anti-solvent (SAS-FB) – a process of precipitating drug particles onto carrier granules. However, in the absence of excipients,…
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Pharmaceutical Applications of Supercritical Fluid Extraction of Emulsions for Micro-Nanoparticle…
Micro-/nanoparticle formulations containing drugs with or without various biocompatible excipients are widely used in the pharmaceutical field to improve the physicochemical and clinical properties of the final drug product. Among the various micro-/nanoparticle production technologies,…
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Effects of crosslinking on the physical solid-state and dissolution properties of 3D-printed…
Crosslinking is an established treatment to alter the physicochemical and functional properties of polymers through the creation of bonds between the polymer chains. Polymers can be crosslinked via radiation in the presence of photo-initiator. The aim of the present study was to formulate 3D-printed…
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Omyanutra® 300 Flash – The all-in-one solution for ODTs and FDTs
The world of nutraceutical tablet formulation is complex and many critical values have to be considered during development - like dissolution properties, shelf-life stability, or exposure to environmental challenges (oxygen, light, humidity and high or low temperatures).
The high number of…
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Combination of lipid nanoparticles and iontophoresis for enhanced lopinavir skin permeation: Impact…
Nanostructured lipid carriers (NLC)-loaded with lopinavir (LPV) were developed for its iontophoretic transdermal delivery. Electronic paramagnetic resonance (EPR) spectroscopy of fatty acid spin labels and differential scanning calorimetry (DSC) were applied to investigate the lipid dynamic behavior…
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