Drug Carrier excipients enhance and interact with the properties of active pharmaceutical ingredients (APIs).
Pharma Excipients
Drug Carrier
Experience the future of Titanium Dioxide replacement: VIVACOAT® free
Discover bright white films and brilliant colors at reasonable weight gains even on your darkest tablet cores!
Enjoy the freedom of choice when banning TiO2 from your tablet coatings:
TiO2- freeTalcum-free Free choice of colors
Low weight gainHigh solid contentNo limits for dark tablet…
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Nanostructured Lipid Carriers Loaded with Lippia sidoides Essential Oil as a Strategy to Combat the…
The emerging pathogen Candida auris is an emerging fungal pathogen that was associated with nosocomial infectious outbreaks. Its worldwide incidence and the emerging multidrug-resistant strains highlight the urgency for novel and effective antifungal treatment strategies. Lippia sidoides essential…
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Design of a thermosensitive ibuprofen-loaded nanogel as smart material applied as anti-inflammatory…
The in vivo ability of thermosensitive nanogel containing ibuprofen for bioadhesion on the surface of teeth submitted to bleaching and drug delivery through dentinal tubules to the dental pulp are evaluated in Wistar rats. Drug-loaded self-assembled oil in water nanoemulsions present droplet size…
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Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children
The higher skin surface area to body weight ratio in children and the prematurity of skin in neonates may lead to higher chemical exposure as compared to adults. The objectives of this study were: (i) to provide a comprehensive review of the age-dependent anatomical and physiological changes in…
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Gum-based nanocapsules comprising naphthoquinones enhance the apoptotic and trypanocidal activity…
Nanoencapsulation is a promising approach to enhance the therapeutic potential of a drug. Herein, three selected naphthoquinone (NTQ) derivatives, based on the IC50 value against Trypanosoma evansi, were encapsulated using gum damar as biocompatible and biodegradable natural gum via…
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Better and greener: sustainable pharmaceutical manufacturing technologies for highly bioavailable…
In the last decades, Green Chemistry has been gaining widespread attention within the pharmaceutical field. It is thus very important to bring more sustainable approaches into the design and manufacture of effective oral drug delivery systems.
This review focuses on spray congealing and…
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Evaluation of the Mucoadhesive Properties of Chitosan-Based Microstructured Lipid Carrier (CH-MLC)
Different mucoadhesive systems have been studied in recent years to increase the residence time of the delivery systems and to prolong the release of the drug. The aim of this work was to evaluate the mucoadhesive properties of chitosan-based Microstructured Lipid Carrier (CH-MLC) with a new…
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Formulation, Characterization, and Cytotoxicity Evaluation of Lactoferrin Functionalized Lipid…
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a very poor prognosis. Its treatment is hindered by a lack of new therapeutic alternatives and the existence of the blood–brain barrier (BBB), which restricts the access of drugs commonly used in ALS, such as riluzole, to the…
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Level A IVIVC for immediate release tablets confirms in vivo predictive dissolution testing for…
A bioequivalence study comparing two fixed dose combination tablets containing 200 mg ibuprofen and 30 mg pseudoephedrine hydrochloride showed bioequivalence for pseudoephedrine AUC and Cmax, but the reference product showed higher Cmax than the test product in fasted conditions. The main difference…
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Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
The oral administration of therapeutic peptides and proteins is favoured from a patient and commercial point of view. In order to reach the systemic circulation after oral administration, these drugs have to overcome numerous barriers including the enzymatic, sulfhydryl, mucus and epithelial…
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