Drug Delivery

Liquid self-nanoemulsifying drug delivery system (L-SNEDDS) of curcumin and quercetin were prepared by dissolving them in isotropic mixture of Labrafil M1944CS®, Capmul MCM®, Tween-80® and Transcutol P®. The prepared L-SNEDDS were solidified using Ganoderma lucidum extract, probiotics and…
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A new tablet system was examined for an intestinal delivery system using hydroxypropyl methylcellulose (HPMC) and shellac. HPMC was incorporated into the inside of the tablet, and shellac was coated on the surface, which was evaluated for its controlled-release property through several dissolution…
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Polygoni cuspidati root is a resveratrol-rich source with anti-inflammatory, angiogenic and neuroprotective effects. The raw material was standardized for the content of resveratrol, for which there is a special justification for administration within the oral mucosa. To improve the solubility of…
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Quality by design (QbD) can also contribute to design, manufacturing, and producing highly finished goods. To better explain the manufacturing processes, the FDA focused QbD in the healthcare industry, based on a comprehensive understanding of how technology and design parameters affect the quality…
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Pulmonary drug delivery is currently the focus of research and development because of its potential to produce maximum therapeutic benefit to patients by directing the drug straight to the lung disease site. Among all the available delivery options, one popular, proven and convenient inhaler device…
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Transdermal administration has gained much attention due to the remarkable advantages such as patient compliance, drug escape from first-pass elimination, favorable pharmacokinetic profile and prolonged release properties. However, the major limitation of these systems is the limited skin…
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Three-dimensional printing (3DP) is predicted to be one of the most progressive innovations within the pharmacy. Nowadays, the use of 3D printing technologies in drug delivery systems has exponentially expanded, due to its potential advantages over customizing drugs in individually adjusted doses.…
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Enhancing cannabinoids’ therapeutic efficacy In our previous technical note, we reported on the encapsulation of CBD vs THC (1) into lipid-based nanoparticles. The work here-in continues on that theme in terms of studying the differences in encapsulating different cannabinoids into the same…
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Micro-/nanoparticle formulations containing drugs with or without various biocompatible excipients are widely used in the pharmaceutical field to improve the physicochemical and clinical properties of the final drug product. Among the various micro-/nanoparticle production technologies,…
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The consumption of foods rich in antioxidants, vitamins, minerals including carotenoids etc. can boost the immune system to help fight off various infections including SARS- CoV 2 and other viruses. Carotenoids have been gaining attention particularly in food and pharmaceutical industries owing to…
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