Electrospinning

Nimodipine is a 1,4-Dihydropyridine type calcium antagonist routinely used to control blood pressure and reduce the risk of secondary ischemia after aneurismal subarachnoid hemorrhage. Additionally, Nimodipine has unique neuroprotective properties. With respect to brain related applications, the…
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Corneal abrasion is a scratch wound on the surface of the anterior segment of the eye, which can predispose a patient to corneal infection and scarring, particularly if the cut penetrates to the deep corneal layers. Here we investigate a novel approach to co-administer an anti-scarring agent and an…
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Nanofiber mats and films are advantageous platforms that can offer unique opportunities as drug carriers in drug delivery technologies. In this research, Artemisone (ART)-loaded polycaprolactone16500-b-α-hydroxy-ω-methoxy poly(ethylene glycol)5000 (PCL-MPEG) nanofibrous nonwovens (NFN), and films…
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Owing to their versatile chemistry, polyaspartamides have recently attracted increased interest in various biomedical uses such as drug delivery systems and scaffolding materials. Their solubility in organic solvents and in water at different values of pH can be fine-tuned by the chemical…
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Presented work focuses on the development of biodegradable polymer nanoparticles loaded with antibiotics as drug delivery systems deposited on electrospun scaffolds for tissue engineering. The innovative ciprofloxacin-loaded poly(DL-lactide-co-glycolide) NPs ensure a continuous slow release and high…
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New strategies based on advanced technologies are highly desired for expanding the applications of biological macromolecules in the applied scientific fields. In the present study, a new kind of core-shell nano depots were designed, in which the shell section was a drug-polymer composite and the…
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Electrospraying or electrohydrodynamic atomisation, i.e. the formation of tiny droplets from a jet of conductive liquid under the influence of an electric field, has been gaining in popularity as a particle engineering technique in recent years. In addition to general benefits for particle…
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Electrospinning (ES) was originally reported in 1899 and the technology has been used since for the fabrication of con- tinuous fibers (Cooley, 1899). Beginning from the 1980s and particularly during the recent decade, the technology has gained increasing attention. Possibly this can be…
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As a result of an aging population, the need for fixed dose combinations in the treatment of cardiovascular diseases, that are easy to swallow and administer, has been growing remarkably. In this work, the feasibility of coaxial electrospraying (CES) was investigated to manufacture in one single…
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Your partner for advanced materials solutions for the pharma industry! With more than a 100 years of cumulated experience, Bioinicia is the first company to have overcome the upscaling issues related to the electrospinning and electrospraying technology with a large-scale, pharma-grade GMP and ISO…
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