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Electrospinning
The Impact of Polymer Mixture Composition on the Properties of Electrospun Membranes for Drug…
Orally dispersible films (ODFs) prepared by an electrospinning are a novel type of pharmaceutical formulation. This dosage form has the potential to be beneficial for small children and the elderly, who can have problems with administration of classical tablets due to the increased risk of choking…
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Fenofibrate loaded nanofibers based thermo-responsive gel for ocular delivery: Formulation…
This research work is to develop nanofiber loaded in -situ gel for the delivery of fenofibrate to the posterior ocular site. Fenofibrate had showed its efficacy in neovascular ocular diseases under clinical studies but its low aqueous solubility makes difficult to develop a suitable ocular…
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Electrospun metal–organic frameworks-loaded nanofibrous carriers for drug delivery systems
Nanotechnology-based-drug-delivery processes are widely applicable for specific drug release. Various pharmaceutical carriers, such as polymeric nano-carriers (solid lipid nanoparticles, micelles, nano-gels/hydrogels, dendrimers, polymeric nano-shapes), vesicular carriers (liposome, noisome),…
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Electrospinning of pullulan-based orodispersible films containing sildenafil
Feasibility of electrospinning in the manufacturing of sildenafil-containing orodispersible films (ODFs) intended to enhance oxygenation and to reduce pulmonary arterial pressure in pediatric patients was evaluated. Given the targeted subjects, the simplest and safest formulation was chosen, using…
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Electrospun composite nanofibers for treating infectious esophagitis
The electrospinning technique enables the convenient fabrication of non-woven fibrous materials with excellent properties such as fine diameters, a large surface area per unit mass, high porosity, high gas permeability, and small pore sizes. Nanofiber applications in healthcare systems continue to…
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Ocular application of electrospun materials for drug delivery and cellular therapies
The constraints of delivering conventional drugs, biologics and cell-based therapeutics to target ocular sites necessitate the fabrication of novel drug delivery systems to treat diverse ocular diseases. Conventional ocular drug delivery approaches are prone to low bioavailability, poor penetration…
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Solid implantable devices for sustained drug delivery
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug administration routes. Oral and injectable drug administration are the most common routes for drug delivery providing peaks of drug concentrations in blood after administration followed by concentration decay…
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Novel long-acting brimonidine tartrate loaded-PCL/PVP nanofibers for versatile biomedical…
The global state of antibiotic resistance highlights the necessity for new drugs that can treat a wide range of microbial infections. Drug repurposing has several advantages, including lower costs and improved safety compared to developing a new compound. The aim of the current study is to…
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The History of Electrospinning: Past, Present, and Future Developments
Electrospinning has rapidly progressed over the past few decades as an easy and versatile way to fabricate fibers with diameters ranging from micrometers to tens of nanometers that present unique and intricate morphologies. This has led to the conception of new technologies and diverse methods that…
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Nano-and Microfabrication Techniques in Drug Delivery – Part 1
Nano-and Microfabrication Techniques in Drug Delivery
See the new book, edited by Dimitrios Lamprou. It brings together technical, clinical, regulatory and industrial perspectives. It provides future prospective and includes the potential clinical applications of nano/microfabrication technologies.…
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