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Electrospinning
Nanofibers in Drug Delivery System
The possible applications of electrospun fibers in drug delivery systems (DDS) are critically examined in this study. Nanofibers are among the most desirable resources in some kind of a variety of scenarios due to their operational capabilities including valuable features for another young…
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Dual-drug delivery of Ag-chitosan nanoparticles and phenytoin via core-shell PVA/PCL electrospun…
Dual-drug delivery systems were constructed through coaxial techniques, which were convenient for the model drugs used the present work. This study aimed to fabricate core-shell electrospun nanofibrous membranes displaying simultaneous cell proliferation and antibacterial activity. For that purpose,…
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Nanostructured Valsartan Microparticles with Enhanced Bioavailability Produced by High-Throughput…
The high-throughput drying and encapsulation technique called electrospraying assisted by pressurized gas (EAPG) was used for the first time to produce nanostructured valsartan within microparticles of excipients. Valsartan, a poorly absorbed and lipid-soluble drug, was selected since it is…
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Solid Dispersion as a Technical Solution to Boost the Dissolution Rate and Bioavailability of Poorly…
Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve the solubility of slowly dissolving drugs. A variety of pharmaceutically compatible additives using different emerging technology is used for preparing SDs. Multiple approaches were designed to prepare SDs by such…
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Fabrication and Characterization of Fast-Dissolving Films Containing Escitalopram/Quetiapine for the…
Major depressive disorder (MMD) is a leading cause of disability worldwide. Approximately one-third of patients with MDD fail to achieve response or remission leading to treatment-resistant depression (TRD). One of the psychopharmacological strategies to overcome TRD is using a combination of an…
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Continuous downstream processing of milled electrospun fibers to tablets monitored by near-infrared…
Electrospinning is a technology for manufacture of nano- and micro-sized fibers, which can enhance the dissolution properties of poorly water-soluble drugs. Tableting of electrospun fibers have been demonstrated in several studies, however, continuous manufacturing of tablets have not been realized…
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Polyvinyl Alcohol/Chitosan Single-Layered and Polyvinyl Alcohol/Chitosan/Eudragit RL100…
A novel nanofiber insert was prepared with a modified electrospinning method to enhance the ocular residence time of ofloxacin (OFX) and to provide a sustained release pattern by covering hydrophilic polymers, chitosan/polyvinyl alcohol (CS/PVA) nanofibers, with a hydrophobic polymer, Eudragit RL100…
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Programmable immune activating electrospun fibers for skin regeneration
Immune cells play a crucial regulatory role in inflammatory phase and proliferative phase during skin healing. How to programmatically activate sequential immune responses is the key for scarless skin regeneration. In this study, an “Inner-Outer” IL-10-loaded electrospun fiber with cascade release…
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Programmable immune activating electrospun fibers for skin regeneration
Immune cells play a crucial regulatory role in inflammatory phase and proliferative phase during skin healing. How to programmatically activate sequential immune responses is the key for scarless skin regeneration. In this study, an “Inner-Outer” IL-10-loaded electrospun fiber with cascade release…
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Electrospraying: A facile technology unfolding the chitosan based drug delivery and biomedical…
Chitosan (CS) a promising biopolymer has been explored for wide biomedical applications using different technologies. Electrospraying is one of the advancing liquid atomization-based techniques rapidly merging in fields of biomedicine, especially in drug delivery and biomedical applications. Recent…
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