Emulsifier

Silymarin, a flavonolignan, derived from Silybum marianum, family Asteraceae has long been used as a hepatoprotective remedy. Silymarin has cytoprotective activities due to its antioxidant property and free radical scavenging activity. The pharmacokinetic studies of past three decades revealed that…
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Apigenin (Apig) is used as a model drug due to its many beneficial bio-activities and therapeutic potentials. Nevertheless, its poor water solubility and low storage stability have limited its application feasibility on the pharmaceutical field. To address this issue, this study developed…
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Abstract: The vast majority of drugs are not designed or developed for pediatric and infant populations. Peptide drugs, which have become increasingly relevant in the past several decades, are no exception. Unfortunately, nearly all of the 60+ approved peptide drugs are formulated for…
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"World Cancer Day every 4 February is the global uniting initiative led by the Union for International Cancer Control (UICC). By raising worldwide awareness, improving education and catalysing personal, collective and government action, they're working together to reimagine a world where millions of…
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Desloratadine (DSL) is an anti-allergic agent but its efficacy is limited with its low dissolution rate and aqueous solubility results in restricted bioavailability. The current study examines the probability of using Kolliphor® 188 (K188) and Pluronic® F127 (P127) as solubility improving agents of…
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Phospholipids are used in many types of formulations, such as fat emulsions, mixed micelles, suspensions, and liposomal preparations for any administration route . Phospholipids are surface-active comprising a polar headgroup and a lipophilic tail. They are used as emulsifier, wetting agent,…
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Providing texture and stability A short video to explain how Gattefossé all-in-one emulsifiers help simplify topical formulations and enable to obtain a wide range of sensorial textures Tefose® 63: widely used oil-in-water emulsifier Gelot™ 64: oil-in-water emulsifier, preferred for high…
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To enhance the dissolution and oral bioavailability of telmisartan (TMS), a poorly water-soluble anti-hypertensive drug, a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) was developed. Amorphous alkalinized TMS (AAT) was formulated into a SMEDDS, composed of Capmul® MCM (oil),…
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Docosahexaenoic acid is a omega-3-fatty acid which together with other long-chain omega-3-fatty acid known to have protective effect against various diseases including hypertension, myocardial infarction, Alzheimer disease, and cancers. Poor bioavailability owning to limited aqueous solubility…
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Insulin is a potent therapeutic molecule used for the treatment of diabetes mellitus type I and late-stage type II. Insulin is usually administered via subcutaneous (s.c.) injection, which bypasses the portal circulation and, in turn, is likely to cause diabetic complications after long-term…
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