Excipients News
News on Excipients
Redispersible dry powders containing nanoencapsulated curcumin increase its antioxidant activity
The present study aimed to develop redispersible spray-dried powders containing curcumin-loaded Eudragit® L100…
Manipulation of solid dosage forms for oral administration to…
Abstract
Background
Children represent a particularly vulnerable demographic in the context of…
Supersolubilization and Amorphization of a Weakly Acidic Drug,…
Abstract
Improvement in drug solubility is a major challenge for developing pharmaceutical products. It was…
Amorphous Polymer–Phospholipid Solid Dispersions for the Co-Delivery…
Curcumin and piperine are plant compounds known for their health-promoting properties, but their use in the…
Optimization of meloxicam-phospholipid complex employing QbD based…
The phospholipids complexation technique is the best solubility enhancement technology, and as a result, many…
Optimising the Aerodynamic Performance of Spray Dried mRNA Lipoplexes…
Introduction
Many respiratory pathogens enter the body through the respiratory tract, the lungs and the…
Off-the-shelf medication transformed: Custom-dosed metoprolol tartrate…
Pharmacies are currently unable to stock proper oral dosage forms for pediatric populations. This leads to…
Paediatric excipient risk assessment (PERA) tool and application for…
Abstract
It is necessary to use a scientifically sound process for excipient risk evaluation, selection, and…
Modelling insertion behaviour of PVP (Polyvinylpyrrolidone) and PVA…
A comprehensive investigation into the effects of nonlinear material behaviour of polymeric (MN) and skin on…
Investigation of magnesium aluminometasilicate (Neusilin US2) based…
Abstract
Background and purpose: Sorafenib tosylate (SFN), a potent multikinase inhibitor, is used for the…
Impact of Hot-Melt Extrusion on Glibenclamide’s Physical and Chemical…
Abstract
This research work dives into the complexity of hot-melt extrusion (HME) and its influence on drug…
Functional dry powders of connexin-containing extracellular vesicles
Extracellular vesicles (EVs) have emerged as a promising drug delivery system. Connectosomes are a specialized…
Three-Dimensional Printing of PVA Capsular Devices for Applications in…
Abstract
The creation of products with personalized or innovative features in the pharmaceutical sector by…
Tailored Sticky Solutions: 3D-Printed Miconazole Buccal Films for…
In this research, 3D-printed antifungal buccal films (BFs) were manufactured as a potential alternative to…
Enhanced Skin Penetration and Efficacy: First and Second Generation…
Skin carcinoma remains one of the most widespread forms of cancer, and its global impact continues to…
MIGLYOL® 812 N & IMWITOR® 742 – Product Spotlights
We invite you to read the below product spotlights of IOI Oleochemicals.
IMWITOR® 742
Chemical Description /…
Should developers choose a cosmetic or pharmaceutical-grade excipient…
As regulations continue to change around the quality and risk of cosmetic- and pharmaceutical-grade…
Development of Orodispersible Tablets with Solid Dispersions of…
Abstract
Poor water solubility is an important challenge in the development of oral patient-friendly solid…
Systematic investigation of the impact of screw elements in continuous…
Twin-screw wet granulation (TSG) is a continuous manufacturing technique either for granules as final dosage…
Selecting appropriate excipients for paediatric dosage form −…
Abstract
Excipients are often the major component of the formulation that critically affect the dosage…
Systematic study to improve the powder feeding performance and…
Abstract
Roller compaction is a widely used continuous dry granulation process in the food and…
Influence of multi-factor interactions on particle growth during…
Abstract
Considering the strong dependence of agglomerate characteristics on various operating parameters,…
Superdisintegrants and their working mechanisms- by DFE Pharma
Superdisintegrants and their working mechanisms
Disintegrants and superdisintegrants are well-known…
Development of a Novel Cyclodextrin–Chitosan Polymer for an Efficient…
Abstract
A novel polymer synthesized by grafting three cyclodextrins onto chitosan was characterized and…
Development of Norelgestromin Dissolving Bilayer Microarray Patches…
Abstract
Microarray patches (MAPs) offer a noninvasive and patient-friendly drug delivery method, suitable…
Critical review on the role of excipient properties in pharmaceutical…
ABSTRACT
Introduction: The pharmaceutical industry is gradually changing batch-wise manufacturing processes…
NEW from MEGGLE: Ready-to-use powder mixture for tabletting –…
Compaction Blend M from MEGGLE
Fast, Reliable, Efficient.
The direct compressible …
Recent advances in modified chitosan-based drug delivery systems for…
Abstract
Recently, transmucosal drug delivery systems (TDDSs) have been extensively studied because they…
An approach for pH-independent release of poorly soluble ionizable…
Hot melt extrudates with combinations of Soluplus® and Aqoat® AS-L or Eudragit® EPO were investigated to…
Reduction of Agglomeration and Production Optimization for Enteric…
Introduction
Pellets are versatile dosage forms for many actives. To control drug dissolution profiles, they…
Inhalable tobramycin EEG powder formulation for treating Pseudomonas…
Pulmonary delivery of antibiotics is an effective strategy in treating bacterial lung infection for cystic…
Comparative Study of Spray-Drying and Freeze-Drying Techniques for…
Abstract
Background: Fenofibrate (FF) is a BCS class II compound whose poor solubility poses challenges in…
Sigachi Film Coatings & Polymer Blends – The Shield of…
Introduction
We are Sigachi, a leading name in the world of Microcrystalline Cellulose (MCC) manufacturing…
Principles, Applications and Limitations of the Liquisolid System of…
Abstract
The liquisolid system of drug delivery continues to find usefulness as a potent means to circumvent…
Eudragit S100 coated iron oxide-chitosan nanocomposites for colon…
The therapeutic effect of 5-amino salicylic acid (5-ASA), a first-line therapeutic agent for the treatment of …
Webinar: Controlled Release for Nutraceuticals
We invite you to our next webinar:
"Controlled Release for Nutraceuticals"
During this webinar…
Cancer cell membrane-modified Soluplus® micelles for gemcitabine…
Pancreatic cancer (PC) is one of the most lethal malignancies worldwide and its incidence is increasing.…
Leveraging 3D-printed microfluidic micromixers for the continuous…
Vesicants are chemical warfare agents (CWAs) capable of causing severe skin damage and systemic toxicity.…
Evaluation of the application of polyethylene glycol 8000 as a…
Solid dispersion formation by hot melt extrusion (HME) is a widely used formulation strategy to improve the…
Towards the prediction of barrel fill level in twin-screw wet…
The barrel fill level is defined as the fraction of the free available volume for a given screw configuration…
Encapsulation of bioactive compounds in foods for diabetics –…
Diabetes is a metabolic disorder characterized by hyperglycemia and is a disease with an increasing…
Advances in active targeting of ligand-directed polymeric nanomicelles…
Many of the utilized drugs which already exist in the pharmaceutical sector are hydrophobic in nature. These…
Characterization of Prototype Gummy Formulations Provides Insight into…
Gummy formulations are considered suitable alternatives to traditional oral dosage forms like tablets and…
An experimental study on flow behaviour in suction filling of…
Die filling is a crucial step in the pharmaceutical tablet manufacturing process. For industrial-scale…
Impact of excipient and blend properties on feeding consistency for…
Purpose
Continuous manufacturing (CM) gains more and more interest in the pharmaceutical industry, which…
A continuous micro-feeder for cohesive pharmaceutical materials
Over the past decade, continuous manufacturing has garnered significant attention in the pharmaceutical…
Development of quercetin-loaded electrospun nanofibers through shellac…
Quercetin possesses multiple biological activities. To achieve efficient colon-specific release of quercetin,…
Emerging role of nanocrystals in pharmaceutical applications: A review…
A significant majority of the 20 approved nanoformulations consist predominantly of nanocrystals (NCs). NCs…
Polysaccharide-based emulsion gels for the prevention of postoperative…
Abstract
Postoperative tissue adhesion is a well-recognized and common complication. Despite ongoing…
3D Printing MicroFactory for Amorphous Solid Dispersion formulations
The Poster was presented at CMAC Summer School 2024
Context and Aim of Work
This study utilised the HUB…