Filler

The present study focuses on the compaction behavior of polymeric excipients during compression in comparison to nonpolymeric excipients and its consequences on commonly used Heckel analysis. Compression analysis at compaction pressures (CPs) from 50 to 500 MPa was performed using a compaction…
Read More...

The 12th APV PBP World Meeting took place from 28 – 31 March 2022 in Rotterdam. There was a poster section at the event where really interesting scientific posters were presented. Therefore we asked the presenting scientists if we could share their work in addition online with the Pharma Excipients…
Read More...

Granulation is employed during production of oral dosage forms to convert small particles of powder ingredients and the active pharmaceutical ingredient (API) into large, free-flowing, dust-free, compressible granules, ensuring uniform distribution of ingredients throughout the resulting mixture.…
Read More...

The 12th APV PBP World Meeting took place from 28 - 31 March 2022 in Rotterdam. There was a poster section at the event where really interesting scientific posters were presented. Therefore we asked the presenting scientists if we could share their work in addition online with the Pharma Excipients…
Read More...

BASF’s premium coprocessed excipient is optimized for your direct compression processes. Our scientists carefully designed this best-in-class product to maximize flowability and tablet strength, with a formulation that has high stability and low sensitivity to overblending. Its round particle shape…
Read More...

Although previously seen as a “winter time” supplement when shorter days mean that exposure to natural sunlight is limited, vitamin D is rapidly becoming a year-round topic for many people as consumers are increasingly aware of its role in supporting the immune system. Able to activate the innate…
Read More...

The influence of the type and ratio of co-process fillers and lubricating excipients on the properties of the final dosage form was studied during the development of the composition and technology for GK-2 tablets dispersed in the oral cavity. The pharmaceutical and technological properties,…
Read More...

Pharmaceutical tablets can be produced on different kinds of presses that may have very different compaction kinematics. Strain rate sensitivity (SRS) is thus an important property for the powders used to produce pharmaceutical tablets. Viscoelasticity is one of the aspects of the SRS and can be…
Read More...

Continuous manufacturing is now considered as a well-established technique by pharmaceutical companies. However, the limited number of filed applications reflects the complexity to translate a science that has been described in many publications to an actual drug product. Process stability…
Read More...

This study determined the feasibility of long-term continuous powder feeding and its effect on the overall process performance. Additionally, quantitative relationships were established between material properties, process settings and screw feeding responses during gravimetric feeding. Twelve…
Read More...