Filler

Inaugural-Dissertation to obtain the academic degree Doctor rerum naturalium (Dr. rer. nat.) submitted to the Department of Biology, Chemistry, Pharmacy of Freie Universität Berlin by Zun Huang Solubility and dissolution rate are essential for the oral absorption and thus bioavailability of…
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Modern pharmaceutical technology still seeks new excipients and investigates the further use in already known ones. An example is magnesium aluminometasilicate Neusilin® US2 (NEU), a commonly used inert filler with unique properties that are usable in various pharmaceutical fields of interest. We…
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With the emergence of quality by design in the pharmaceutical industry, it becomes imperative to gain a deeper mechanistic understanding of factors impacting the flow of a formulation into tableting dies. Many flow characterization techniques are present, but so far only a few have shown to mimic…
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The material properties of excipients and active pharmaceutical ingredients (API's) are important parameters that affect blend uniformity of pharmaceutical powder formulations. With the current shift from batch to continuous manufacturing in the pharmaceutical industry, blending of excipients and…
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In this study, an empirical predictive model was developed based on the quantitative relationships between blend properties, critical quality attributes (CQA) and critical process parameters (CPP) related to blending and tableting. The blend uniformity and API concentration in the tablets were used…
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Co-processing is commonly used approach to improve functional characteristics of pharmaceutical excipients to become suitable for tablet production by direct compression. This study aimed to improve tableting characteristics of lactose monohydrate (LMH) by co-processing by fluid-bed melt granulation…
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Stability studies are an integral part of the drug development process for any drug product. In addition to monitoring chemical degradation, the physical stability of a drug product must also be evaluated to ensure that the drug release and performance is not affected by storage. In this study,…
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galenIQ™ is a sweet-tasting water soluble filler binder derived from sugar beet. It is available in several different morphological forms which are suitable for the formulation and manufacture of oral solid dosage forms including tablets, effervescents, medicated lozenges and powder blends for…
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How can Kollitab™ DC 87 L help you? Superior flowability High tablet strength at broad compression forces Fast disintegration Order Kollitab™ DC 87 L here! Key benefits Manufacturing Enables fast tablet development Simplifies formulation development Reduces…
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Easy to use and with improved technical properties, BENEO’s galenIQ™ 721 filler-binder optimizes the production of fizzy tablets and powders To improve the taste and stability of effervescent tablets and powders, BENEO presents galenIQ™ 721. This filler-binder enables pharmaceutical and…
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