Filler

Many patients and consumers have difficulty to swallow standard-sized tablets. For these persons, a more convenient form is to provide the medicine or supplement as an effervescent tablet or effervescent powder! A non-hygroscopic water-soluble filler binder is required, however, in order to make…
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Q: When choosing a pharmaceutical excipient, what should I pay attention to and what’s currently driving the excipients market? A: Dr Maj-Britt Cepok, Head of Business Development Pharma at BENEO, says: The global pharmaceutical excipients market is expected to reach USD 10.6 billion by 2026.…
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Obtaining orodispersible tablets (ODT) containing substances from the 2nd Biopharmaceutical Class has raised concerns as the dissolution test is challenging. This study aimed to select suitable excipients for developing orodispersible tablets containing cannabidiol (CBD) by direct compression…
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The aim of this work was to develop anti-stress compressed lozenges containing 100 mg of glycine and 250 mg of magnesium citrate obtained by the direct compression method. To choose optimal excipient composition providing the sufficient pharmaco-technical properties of the tablet blend, mechanical…
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JRS cellulose products come in various shapes and structures. For their customers, it is not only essential, to receive excellent functionality in their applications, but also to understand how they can incorporate the fibers in their production lines. In large scale processes, parameters like…
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Background: Theacrine (1,3,7,9-tetramethyluric acid, TC) is a purine alkaloid rich in the tender leaves of an unusual Chinese tea known as Kucha. TC possessed diverse pharmacological activity including antioxidative, anti-inflammatory, analgesic and anti-depressive effects. Aim In this work,…
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Adjusting the thermal response properties of a polymeric compound can significantly improve the usability in a selective laser-sintering process. As previously shown, combining a precise amount of coarse and narrow size distribution fine calcium carbonate fillers results in a potential optimization…
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Granular materials are part of the design, production and final products of different industrial sectors. Powder flowability is a major topic in manufacturing and transport as it is closely related to process feasibility. Nonetheless, the flows of granular materials are not easy to describe or…
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Binder jetting is an additive manufacturing technique that creates three-dimensional constructs from a powder feedstock. It is used by several industries, including pharmaceuticals. This additive approach to manufacture provides several functional benefits that are not easily achievable using…
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A single-tablet-scale mixing process, being part of a setup for the production of individualized tablets, is developed and studied. The process relies on the principle of vibratory mixing to achieve a homogeneous powder blend in the order of seconds. To investigate the mixing performance under…
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