Filler excipients are used to increase the volume of the material to enable easier processing of the ingredients and make it into a size suitable for consumption. Moreover, they can stabilize the product and help during manufacturing.
Pharma Excipients
Filler
Design, Characterization and Evaluation of Quick Dissolving Matrix BARETab® ODT Tablet In…
Abstract
The oral dissolving tablets is defined as one, which has drug in it and when placed on tongue dissolves completely within a limited span of time, without additional requirement of water. Drug is released, dispersed in the saliva and swallowed and subsequently absorbed in the…
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Study of Powder and Tableting Functionality Towards Evaluation and Characterisation of BARETab® PH…
Abstract
BARETab® PH is a multi-functional ready to use premixed, co-processed ingredient for direct compression (DC) formulations. It is a combination of selective, largely used excipients for DC. Direct compression is the most widely used tableting method because of the simple manufacturing…
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The effect of polymeric binder type and concentration on flow and dissolution properties of SMEDDS…
Self-microemulsifying drug delivery systems (SMEDDS) are lipid-based formulations, designed to improve the solubility of poorly-water soluble drugs. Mesoporous silica is frequently used for SMEDDS solidification by various techniques. One of them is wet granulation, which enables achieving both high…
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Comparison of properties on Orally Disintegrating Tablets (ODTs) produced by direct compression or…
Abstract
Orally disintegrating tablets (ODTs) is a popular drug delivery system as they dissolve in the mouth, usually within seconds which enables easy medication for patients with problem swallowing. In this thesis properties of ODTs were compared when produced with direct compression of the…
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One Step In Situ Co-Crystallization of Dapsone and Polyethylene Glycols during Fluidized Bed…
Abstract
Several studies have demonstrated the feasibility of in situ co-crystallization in different pharmaceutical processes such as spray drying, hot melt extrusion, and fluidized bed granulation (FBG) to produce co-crystal-in-excipient formulations. However, no previous studies have examined…
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The effect of excipients on oral lyophilizates quality attributes
Pharmaceutical industry is constantly focused on researching patient-centered dosage forms that can maximize the therapeutic potential of an active pharmaceutical ingredient, as for example orodispersible form. The main advantage of orodispersible dosage forms is that they are suitable for patients…
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A technical note: Characterization and evaluation of novel, ready to use coprocessed excipient in…
Abstract
A tablet is composed of different excipients and drug. All excipients have different properties with applications. Excipients are used to provide bulk and help to bind API into a dosage form, excipient should be inert in nature with respectable physical properties. Because the physical…
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Comparing the Performance of Raman and Near-Infrared Imaging in the Prediction of the In Vitro…
In this work, the performance of two fast chemical imaging techniques, Raman and near-infrared (NIR) imaging is compared by utilizing these methods to predict the rate of drug release from sustained-release tablets. Sustained release is provided by adding hydroxypropyl methylcellulose (HPMC), as its…
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Evaluation of tricalcium citrate as a direct compressible diluent using the SeDeM Expert Diagram…
ABSTRACT
Oral administration of medicine is one of the most common delivery routes still in use today. Various dosage forms are administered via the oral route including tablets, capsules, syrups, solutions and emulsions. Tablets constitute a large part of orally available dosage forms due to ease…
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Florite® R as a model for incorporation of essential oils as active substances into a solid dosage…
Application of essential oils in modern medicine has a limited use due to its specific physico-chemical properties which can make them extremely unsuitable for the formulation of stable pharmaceutical forms. The aim of this study was to develop robust hard capsules formulation with natural essential…
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