Filler

The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD) approach. A randomized Box–Behnken experimental design was used to characterize the effect of the critical factors, such as filler (MCC/Mannitol) ratio, mixing time,…
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Mesoporous carriers are a convenient choice for the solidification of self-microemulsifying drug delivery systems (SMEDDS) designed to improve the solubility of poorly water-soluble drugs. They are known for high liquid load capacity and the ability to maintain characteristics of dry, free-flowing…
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Introduction Oral disintegrating tablets (ODTs) are patient-centric drug delivery systems (for example, for pediatrics, geriatrics, and psychiatric patients with dysphagia) designed to increase patient compliance. ODTs are preferred to classic dosage forms (swallowable / chewable / suckable…
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Abstract Compounded tablets are solid dosage forms that contain active pharmaceutical ingredients that are usually formulated with suitable pharmaceutical excipients. Fillers are inert ingredients used as bulking agents that can affect the physical properties of the final compounded tablet. The…
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This study investigated the phase stability of liquid mixtures and composite gels properties of de-structured waxy potato starch (DWPS) and whey protein isolate (WPI). The DWPS are physically-modified starches treated at 120, 140 and 150 °C for 30 min under constant shear. The composite gels (13%…
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MEGGLE is a pioneer in co-processing technologies that allow simple, robust formulation development and manufacture. Through co-processing, MEGGLE developed highly functional excipients possessing unique qualities for directly compressible immediate and sustained release pharmaceutical solid dosage…
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FlowLac by MEGGLE is directly compressible lactose having a spherical agglomerate shape, consisting of small alpha-lactose monohydrate crystals bound by amorphous lactose. It  is produced by spray-drying a suspension of fine milled alpha-lactose monohydrate crystals in a solution of lactose. When…
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Objective The aim of this study was to use an alternative granulation technique, solventless roll compaction, and to investigate the effect of the roll compaction pressure on the properties of granules and high-drug-loaded (80%, w/w) immediate release piracetam tablets. Significance…
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RetaLac® by MEGGLE is a co-processed excipient comprising of equal parts of milled alpha-lactose monohydrate and hypromellose (USP substitution type 2208) with a nominal viscosity of 4000 cps. A specialized spray-agglomeration process generates textured, highly structured particles with d50 in…
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Excipients for direct tabletting and  granulation Product Description Lactose Overview Lactose is a disaccharide of glucose and galactose obtained from the whey fraction of bovine milk. Depending on the temperatures used to crystallize and dry the lactose solution, it may be produced in…
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