Pharma Excipients
Film former
Methodology to estimate the break force of pharmaceutical tablets with curved faces under…
This paper develops a methodology to estimate the break force of curved faced tablets under diametrical compression. Common excipients used in pharmaceutical tablet formulations, including microcrystalline cellulose, calcium phosphate and mannitol as well as their mixtures were characterised.…
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Comparative study on disintegration methods for oral film preparations
13. September 2018
Orodispersible films (ODFs) provide high application comfort due to rapid disintegration in the oral cavity. They increasingly found the approval of pharmaceutical research and development and were added to the European Pharmacopeia in 2012. The European Pharmacopeia explicitly…
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3D printed drug products: Non-destructive dose verification using a rapid point-and-shoot approach
08. August 2018
Three-dimensional printing (3DP) has the potential to cause a paradigm shift in the manufacture of pharmaceuticals, enabling personalised medicines to be produced on-demand. To facilitate integration into healthcare, non-destructive characterisation…
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Preventing Film Coating Problems by Design
"Common defects in tablet film coating can be minimized by effective design of the tablet core and the coating process." Stuart C. Porter in Pharmaceutical Technology
Film coatings on pharmaceutical tablets provide a broad range of functionalities, and the coating formulation and process are…
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Ideal Cures Launches Two New Film Coating Products INSTACOAT QD and INSTACOAT T2F at the 2nd FDD…
10. July 2018
In a joint initiative, Ideal Cures - India's foremost film-coating and pharmaceutical excipient company - along with Express Pharma, India's leading pharmaceutical and biotechnology publication, in their endeavor to recognize and appreciate FR&D scientists…
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Improved HPMC films by incorporation of amylose-sodium palmitate
07. February 2018
Abstract
Polymer film blends of hydroxypropyl methylcellulose (HPMC) and amylose-sodium palmitate inclusion complexes (Na-Palm) were produced with no plasticizer, and were observed to have improved physical and gas barrier properties as compared with…
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Optimization of film-coating formulation containing a novel low molecular weight hypromellose to…
28. April 2017 Abstract In recent years, a novel low molecular weight hypromellose (hypromellose 2906, VLV hypromellose) was developed to improve tablet-coating process and lower costs in the pharmaceutical industry. Such VLV…
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ANOVEL FILM COATING FORMULATION TO MINIMIZE COLOUR FADING
12. December 2016 ANOVEL FILM COATING FORMULATION TO MINIMIZE COLOUR FADING Introduction It is common practice within the pharmaceutical industry to enhance the aesthetic appearance of dosage forms by using suitably colored film…
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The central role of excipients in drug formulation
Active substances are rarely administered alone. For example, levothyroxine, a synthetic form of the thyroid hormone, indicated in the treatment of hypothyroidism, is administered at a very low dosage, ranging from 15 μg to 200 μg. These very small amounts of powder mean that it is not possible…
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