Film former

Drug hydrolytic degradation, caused by atmospheric and inherent humidity, significantly reduces the therapeutic effect of pharmaceutical solid dosages. Moisture barrier film coating is one of the most appropriate and effective approaches to protect the active pharmaceutical ingredients (API) from…
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An optical method of experimentally quantifying the coating progress in a laboratory prismatic spouted bed is presented. Microcrystalline cellulose particles (Cellets) with size dp = 0.57 mm are used as core material. Waterborne coating suspensions with methylene blue as a dye are used and…
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To date, the lack of age-appropriate medicines for many indications results in dose manipulation of commercially available dosage forms, commonly resulting in inaccurate doses. Various printing technologies have recently been explored in the pharmaceutical field due to the flexible and precise…
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Wurster coater was utilized for coating glass beads with HPMC/PEG. The effects of design and operating parameters on the coating process were evaluated. It was found that the pressure drop decreases when spraying the coating solution into the bed, indicating that spraying prevents the particles…
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Solvent-free hot melt coating (HMC) provides a safer and more economic process compared to the conventional solvent coating techniques. However, drug release instability and the lack of fundamental understanding on it are limiting factors for application of HMC for industrial productions. In this…
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France will ban Titanium dioxide as an additive in food in France from January 1, 2020, the Ministries of Ecology and Economy have said. The government has decided to ban "as a precaution" foodstuffs containing titanium dioxide (TiO2, an additive known as E171) as from 1 January 2020, the two…
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Warfarin is a narrow therapeutic index drug that requires personalized dosing which is currently not achieved by the marketed products. Further, pediatric and geriatric patients may face swallowing problems with solid oral dosage forms. To face these issues, the aim of the present study was to…
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Polymeric films were prepared based on chitosan and its blends with poly(2-ethyl-2-oxazoline) by casting from aqueous solutions. These materials were characterised using a number of physicochemical techniques, including Fourier-transform infrared spectroscopy, thermal gravimetric analysis,…
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Recently, various additive manufacturing (3D printing) approaches have been employed to fabricate dressings such as film scaffolds that possess well-defined architecture and orientation at the micro level. In this study, crosslinked chitosan (CH) based film matrices were prepared using 3D printing…
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Considering the advantages of orally disintegrating films as alternative pharmaceutical dosage forms, the objective of this work was to develop and evaluate different formulations of orally disintegrating films based on pre-gelatinised starch (%S) and hydroxypropyl methylcellulose (%HPMC), with…
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