Gelatin is a versatile and widely used ingredient in the pharmaceutical industry, where it serves various critical functions in the formulation and production of pharmaceutical products. This article explores the sources, manufacturing process, and applications of pharmaceutical gelatin, shedding light on its significance in pharmaceuticals.
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Gelatin
PLGA/Gelatin-based electrospun nanofiber scaffold encapsulating antibacterial and antioxidant…
A full-thickness or hard-to-heal wound pose a significant challenge in clinical feilds. These wounds are very prone to microbial infection, lead to an elevated level of reactive oxygen species, and require a skin regeneration product for rapid healing. Considering these issues, we developed…
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The Quest for Child-Friendly Carrier Materials Used in the 3D Semi-Solid Extrusion Printing of…
This work gives a brief overview of carrier materials currently used in pharmaceutical studies on the three-dimensional (3D) semi-solid extrusion (SSE) printing of medicines for pediatrics. The suitability of using these carrier materials in pediatric formulations, concerning safety and toxicity,…
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Preparation, characterization, and in vitro release of microencapsulated essential oil…
Oregano essential oil (EO)–loaded pellets were prepared using calcium phosphate substrates of different specific surface areas (Sw) and as binders EO in water emulsions with low or high EO content, stabilized with polysaccharides (PSC) or a combination of PSC-Eudragit® L100-55 (PSC-PLM)…
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Development, in vitro Evaluation, and in vivo Study of Adhesive Buccal Films for the Treatment of…
Objective: Development and evaluation of bucco-adhesive films of Gliclazide for pediatric use.
Methods: Sixteen films were formulated using a different combination of Gelatin, Hydroxy propyl methyl cellulose (HPMC), polyvinyl alcohol, Hydroxy propyl cellulose (HPC), chitosan, polyethylene glycol,…
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In Situ Co-Amorphization of Olanzapine in the Matrix and on the Coat of Pellets
In situ amorphization is a promising approach, considered in the present work, to enhance the solubility and dissolution rate of olanzapine, while minimizing the exposure of the amorphous material to the stress conditions applied during conventional processing. The production of pellets by…
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Buccal films: A review of therapeutic opportunities, formulations & relevant evaluation…
The potential of the mucoadhesive film technology is hard to ignore, owing to perceived superior patient acceptability versus buccal tablets, and significant therapeutic opportunities compared to conventional oral drug delivery systems, especially for those who suffer from dysphagia. In spite of…
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Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues
Eutectogels (Egels) are an emerging class of soft ionic materials outperforming traditional temperature-intolerant hydrogels and costly ionogels. Due to their excellent elasticity, non-volatile nature, and adhesion properties, Egels are attracting a great deal of interest in the biomedical space.…
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Innovations in Chewable Formulations: The Novelty and Applications of 3D Printing in Drug Product…
Since their introduction, chewable dosage forms have gained traction due to their ability to facilitate swallowing, especially in paediatric, geriatric and dysphagia patients. Their benefits stretch beyond human use to also include veterinary applications, improving administration and palatability…
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Hypromellose – Collagen hydrogels/sesame oil organogel based bigels as controlled drug delivery…
The search for novel strategies to formulate bioactive molecules for topical administration is a matter of permanent interest in the pharmaceutical field. As a contribution, the present work deepens the bigels, i.e., matrix-in-matrix systems resulting from mixing a hydrogel and an organogel.…
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Eudragit® L100/Polyvinyl Alcohol Nanoparticles Impregnated Mucoadhesive Films as Ocular Inserts for…
The fast elimination of drugs from the cornea is one of many challenges associated with the topical administration of conventional dosage forms. The present manuscript aimed to prepare modified-release inserts containing erythromycin (ERY) to enhance drug delivery and address the aforementioned…
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