Gelatin is a versatile and widely used ingredient in the pharmaceutical industry, where it serves various critical functions in the formulation and production of pharmaceutical products. This article explores the sources, manufacturing process, and applications of pharmaceutical gelatin, shedding light on its significance in pharmaceuticals.
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Gelatin
Biomedical Applications of Biodegradable Polymers in Wound Care
According to the World Health Organization, it is estimated that 180,000 deaths occur annually due to burns. In the United States, it is expected that chronic wounds (e.g., diabetic and pressure ulcers) affect 6.5 million people. Thus, skin lesions are a public health problem that imposes the…
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Orodispersible Film Loaded with Enterococcus faecium CRL183 Presents Anti-Candida albicans Biofilm…
Background: Probiotic bacteria have been emerging as a trustworthy choice for the prevention and treatment of Candida spp. infections. This study aimed to develop and characterize an orodispersible film (ODF) for delivering the potentially probiotic Enterococcus faecium CRL 183 into the oral cavity,…
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Effects of Different Capsule Types for Oral Application of Active Substances – Investigations with…
1.1. Background: A capsule is a solid dosage form that delivers a defined dose of an active ingredient. Most capsules are made for oral application by mouth with subsequent swallowing. Capsule materials for the shell are not only of importance for the release of active ingredients, but should also…
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Physico-chemical Modification of Gelatine for the Improvement of 3D Printability of Oxidized…
This work explored 3D bioplotting to mimic the intrinsic hierarchical structure of natural articular cartilage. Alginate dialdehyde-gelatine (ADA-GEL) was used as a hydrogel ink to create hierarchically ordered scaffolds. In comparison to previously reported ADA-GEL compositions, we introduce a…
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Controlled release of pharmaceutical agents using eutectic modified gelatin
Deep eutectic solvent (DES) is a class of ionic liquids, consisting of a mixture generally formed by combining hydrogen bond donors (HBDs) such as alcohols, amides and carboxylic acids with various quaternary ammonium salts. The decrease in melting points of the constituents is due to the charge…
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Challenges of Dissolution Methods Development for Soft Gelatin Capsules
Recently, the development of soft gelatin capsules (SGCs) dosage forms has attracted a great deal of interest in the oral delivery of poorly water-soluble drugs. This is attributed to the increased number of poorly soluble drugs in the pipeline, and hence the challenges of finding innovative ways of…
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Better Medicines for Older Patients: Considerations between Patient Characteristics and Solid Oral…
Oral drug administration provided as solid oral dosage forms (SODF) remains the major route of drug therapy in primary and secondary care. There is clear evidence for a growing number of clinically relevant swallowing issues (e.g., dysphagia) in the older patient population, especially when…
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3D printing of gummy drug formulations composed of gelatin and an HPMC-based hydrogel for pediatric…
The 3D printing of drug formulations is a promising method for preparing tailored medicines following the approval of 3D printed tablets by the US FDA in 2015. Appropriate dosage forms for pediatric patients are deficient because drugs have been developed for mainly adult patients.
Here, we…
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LYCAGEL™ – Roquette’s Innovative Plant-Based Solution Unlocks Possibilities for Veggie Softgel…
Market-first plant-based softgel system provides a strong alternative to gelatin for nutraceutical and pharmaceutical manufacturers and marketers of softgel products
GENEVA, Illinois. (November 18, 2020) - Roquette, a global leader in plant-based ingredients, pioneer of plant proteins and…
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The progress on sulfhydryl modified polymers with regard to synthesis, characterization and…
The concepts of mucoadhesion and mucoadhesive polymers were introduced in the 20th century, leading to several advantages. These included enhanced drug absorption and extended residence at specific site of action. Polymeric excipients underwent chemical modification with sulfhydryl groups on the…
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