Gellan Gum is a versatile polysaccharide that has found extensive applications in various industries, including the pharmaceutical sector. Known for its unique rheological properties and gelling abilities, gellan gum has become a popular choice for pharmaceutical formulations, contributing to the stability and performance of various drugs.
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Gellan Gum
An evaluation of film coating materials and their predicted oro-esophageal gliding performance for…
Oral drug therapy is generally provided in the form of solid oral dosage forms (SODF) that have to be swallowed intact and move throughout the oro-esophageal system until reaching the stomach. Previous studies have provided evidence that the surface characteristics of SODF play an important role…
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The use of natural gums to produce nano-based hydrogels and films for topical application
Natural gums are a source of biopolymeric materials with a wide range of applications for multiple purposes. These polysaccharides are extensively explored due to their low toxicity, gelling and thickening properties, and bioadhesive potential, which have sparked interest in researchers given their…
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Innovations in Chewable Formulations: The Novelty and Applications of 3D Printing in Drug Product…
Since their introduction, chewable dosage forms have gained traction due to their ability to facilitate swallowing, especially in paediatric, geriatric and dysphagia patients. Their benefits stretch beyond human use to also include veterinary applications, improving administration and palatability…
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Spermidine Crosslinked Gellan Gum-Based “Hydrogel Nanofibers” as Potential Tool for the Treatment of…
Purpose: Aim of the work was to develop a potential neural scaffold, endowed with neuroprotective and neuroregenerative potential, to be applied at the site of nervous tissue injuries: nanofibers, consisting of gellan gum (GG), spermidine (SP) and gelatin (GL), were prepared via electrospinning. SP…
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Dual Drug Loaded Lipid Nanocarrier Formulations for Topical Ocular Applications
Introduction:
Untreated ocular infections can damage the unique fine structures of the eye with possible visual impairments and blindness. Ciprofloxacin (CIP) ophthalmic solution is prescribed as first-line therapy in ocular bacterial infections. Natamycin (NT) ophthalmic suspension is one of the…
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Carbohydrates Used in Polymeric Systems for Drug Delivery: From Structures to Applications
Abstract
Carbohydrates, one of the most important compounds in living organisms, perform numerous roles, including those associated with the extracellular matrix, energy-related compounds, and information. Of these, polymeric carbohydrates are a class of substance with a long history in drug…
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Fabrication Methods and Form Factors of Gellan Gum-Based Materials for Drug Delivery and Anti-Cancer…
Despite the success of cancer therapeutics, off target cell toxicity prevails as one of the main challenges of cancer treatment. Exploration of drug delivery methods is a growing field of research, which involves a variety of materials and processing techniques. A natural polymer, gellan gum…
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Development and in-vitro in-vivo characterization of in-situ gelling sustained-release nevirapine…
Nevirapine is a BCS class-II drug used in the treatment and prevention of HIV/AIDS, specifically HIV-1. This study was aimed to develop and evaluate a novel pH-responsive in-situ gelling sustained-release nevirapine pediatric suspension (SRNPS) for treatment and prevention of mother-to-child…
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Evaluation of Gelling Behavior of Natural Gums and their Formulation Prospects
Purpose: Gums and polymers can be found abundantly in the nature from various plants, microbial and marine sources. Their physical and functional characteristics can be customized according to its application in product development. The purpose of this study is to determine the potentiality of…
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Better Medicines for Older Patients: Considerations between Patient Characteristics and Solid Oral…
Oral drug administration provided as solid oral dosage forms (SODF) remains the major route of drug therapy in primary and secondary care. There is clear evidence for a growing number of clinically relevant swallowing issues (e.g., dysphagia) in the older patient population, especially when…
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