Glidant

Abstract Granulation is a size-enlargement process by which small particles are bonded, by means of various techniques, in coherent and stable masses (granules), in which the original particles are still identifiable. In wet granulation processes, the powder particles are aggregated through the use…
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Data from wall friction testing and physical property characterization of over one hundred pharmaceutical powders, blends, and granulations has been analyzed. The analyses focused on data for stainless steel surfaces with the most common finishes for pharmaceutical powder processing equipment,…
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The causes of atypical nitrogen adsorption isotherm features of commercial magnesium stearate grades have been investigated through a combination of alternative adsorbates and variation of analytical conditions. Atypical features have previously been identified as having poor linearity of adsorption…
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mceODT is highly effective semi-natural multicomponent, multifunctional co-processed excipient, designed for orally disintegrating tablets and chewable produced by method of direct compression. It is a homogenous mixture composed of filler (mixture of natural and semi-natural starches with polyols)…
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In this video Chris Moreton gives an interesting insight on pharmaceutical excipients. 
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It is of great importance to get a deeper understanding of the binding behaviour and functionality of different types of dry binders, since dry binders are crucial to ensure appropriate properties of dry granules and tablets. Based on previous studies, the most effective dry binders of chemically…
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What is an orally disintegrating dosage form? An orally disintegrating tablet is a novel formulation that dissolves in the saliva within a few seconds and without requiring of drinking additional water. This dosage form is a powerful way to deliver active drugs ingredients because it has many…
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Appropriate lubrication is important in tablet manufacturing as it lowers punch sticking propensity and protects tooling by reducing friction between die wall and tablet during tablet manufacturing. Most commercial lubricants negatively impact tabletability and dissolution. A delicate balance is…
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The selection of the excipients(s) for a tablet formulation should take into account the API properties, process, target formulation and potential impact on the formulation. Some of those API properties can be Dose Particle Size Flow Properties Bulk Density Moisture…
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