Pharma Excipients
Inorganic Chemicals
Development of a Solid Supersaturated Self-Nanoemulsifying preconcentrate (S-superSNEP) of…
Recrystallization of drug and incomplete drug release from liquisolid formulation are two major hurdles in the development of a supersaturated self-nanoemulsifying drug delivery system. The aim of this research work was to develop a solid supersaturated self-nanoemulsifying drug delivery system of…
Read More...
Read More...
PharSQ Spheres – Calcium Phospate Starter Pellets
Drug layering on starter pellets is a standard technology to achieve multiparticulate dosage forms. The most widely used are still sugar spheres / non-pareils but also neutral pellets made of microcrystalline cellulose such as Cellets are applied. Although not a lot of new starter pellets have come…
Read More...
Read More...
Conformational polymorphic changes in the crystal structure of the chiral antiparasitic drug…
Praziquantel is an antiparasitic drug used for decades. Currently, the praziquantel commercial preparation is a racemic mixture, inwhich only the levo-enantiomer possesses anthelmintic activity. The knowledge of its properties in the solid state and other chemical-physical properties is necessary…
Read More...
Read More...
Setting Specifications for Excipients – Stimuli Article & Survey
14. August 2018
Setting Specifications for Excipients - Stimuli Article & Survey
A USP Stimuli article to the revision process, titled, “The Complexity of Setting Specifications for Excipient Composition and Impurities”, is published in Pharmacopeial Forum (PF) 44(3)…
Read More...
Read More...
Discover calcium phosphates functionalities in direct compression formulations
04. January 2018
Calcium phosphates have been used in the pharmaceutical technology for many years. They have many physical and chemical properties that make them ideal candidates for the production of solid oral dosage forms. They are mainly used as fillers in order to bulk up…
Read More...
Read More...
Solid formulation of a supersaturable self-microemulsifying drug delivery system for valsartan
11. December 2017
Abstract
In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMEDDS) composed of VST (80 mg),…
Read More...
Read More...
Mouthfeel of ODT with Functionalized Calcium Carbonate
11. October 2017 Orally disintegrating tablets (ODT) are comfortable and safe drug delivery methods beneficial for all age groups of patients. ODTs are characterized by fast disintegration, high physical stability, taste masking…
Read More...
Read More...
Spray-congealed Solid Lipid Microparticles for the controlled Bisphosphonates release
07. October 2017 Theaim of this work was to develop an innovative drug delivery system potentially useful for the local delivery of Bisphosphonates to bone tissue. We propose the use of Solid Lipid Microparticles (MPs),up to now mainly…
Read More...
Read More...
Influence of calcium carbonate and sodium carbonate gassing agents on pentoxifylline floating…
11. September 2017
Purpose
This study was to design and evaluate effervescent floating tablets with sustained release behaviour. Pentoxifylline is a water-soluble model drug with a short half-life, consequently developing sustained release preparations would be…
Read More...
Read More...
Mesoporous Biomaterials: a Lexicon and Structured Bibliography of Reviews
07. June 2017 Accessing mesoporous and nanostructure biomaterial information can be particularly time consuming and problematic due to the interdisciplinary nature of the field. Relevant papers can be found across a broad range of…
Read More...
Read More...