Pharma Excipients
Inorganic Chemicals
Characterization of new functionalized calcium carbonate-polycaprolactone composite material for…
24. May 2017 Abstract A new mineral–polymer composite (FCC-PCL) performance was assessed to produce complex geometries to aid in development of controlled release tablet…
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Nanoporous Calcium Carbonate-Based Substrates for the Controlled Delivery of Functional Materials
24. May 2017
The overall aim of this project was to study `functionalised' calcium carbonates (FCCs) for use as a carrier for the controlled release of `actives,' by permeation and diffusion, and is being proposed as an environmentally friendly and non-toxic…
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Budenheim site GMP certified for phosphate excipients
25. March 2017 Chemische Fabrik Budenheim site receives EXCiPACT GMP Certification as pharmaceutical excipient suppliers Speciality products and phosphates company, Budenheim, has received an GMP/GDP Certificate for…
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Characterisation of the Pore Structure of Functionalised Calcium Carbonate Tablets by Terahertz…
12. March 2017 Abstract Novel excipients are entering the market to enhance the bioavailability of drug particles by having a high porosity and thus providing a rapid liquid uptake and disintegration to accelerate subsequent…
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The Utilization of Surface Free Energy for Predicting Flowability of Filler-Lubricant or…
31. January 2017
The aim of this study was to apply the knowledge of surface free energy for the flowability prediction of pharmaceutical excipients. In order to predict the flowability, the spreading coefficient was calculated from the surface free energy of each material using Wu's…
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Functionalised calcium carbonate: a next-generation mineral excipient
11. October 2016
Orally disintegrating tablets (ODTs) are a preferred dosage form compared with conventional tablets because of the numerous advantages they offer, such as rapid dissolution and fast onset of action.
To maintain the porous structure needed for fast dispersion, most…
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Mechanism by Which Magnesium Oxide Suppresses Tablet Hardness Reduction during Storage
14. September 2016
Abstract
This study investigated how the inclusion of magnesium oxide (MgO) maintained tablet hardness during storage in an unpackaged state. Tablets were prepared with a range of MgO levels and stored at 40°C with 75% relative humidity for up to 14 d. The…
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Coatless alginate pellets as sustained-release drug carrier for inflammatory bowel disease treatment
28. July 2016
Abstract
Conventional alginate pellets underwent rapid drug dissolution and failed to exert colon targeting unless subjected to complex coating. This study designed coatless delayed-release oral colon-specific alginate pellets for ulcerative colitis…
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ICH Q3D practical implementation challenges – a dual perspective -Manufacturer and excipient…
28. April 2016
Presentation by Dr Andrew Teasdale AstraZeneca
IPEC Europe Excipients Forum - Making Pharmaceutics 2016
Link to pharm tech article (March 2015)
IPEC Elemental Impurities Lette & Template (incl. Daily Intake Calculator)
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Multiple-unit tablet of probiotic bacteria for improved storage stability, acid tolerability, and in…
28. April 2016
Abstract: The aim of this study was to formulate probiotics-loaded pellets in a tablet form to improve storage stability, acid tolerability, and in vivo intestinal protective effect. Bacteria-loaded pellets primarily prepared with hydroxypropyl methylcellulose…
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