Isomalt

We had a webinar with the experts from BENEO to find out more on galenIQ™. See here some answers to the questions asked from participants of the webinar and have a look at the full webinar recording.  galenIQ™ is a soluble filler and binder that can be used to meet many of the current trends and…
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Continuous manufacturing is an important element of future manufacturing solutions enabling for both high product quality and streamlined development process. The increasing possibilities with computer simulations allow for innovating novel mixing principles applicable for continuous manufacturing.…
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Enabling formulations often depend on functional excipients. However, the question remains whether excipients regarded as standard establish similar interactions and subsequently improvement of solubility when employed at unusual manufacturing process conditions. In this study, compaction of API…
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The typical excipients used as bulking agents and lyoprotectants for freeze-drying are usually limited to only a few selected substances, such as sucrose and mannitol. Considering the sheer diversity amongst proteins, it is doubtful that this limited choice should, in every case, provide the best…
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This study aims to examine the contribution of nanoporous silica entrapped lipid-drug complexes (NSCs) in improving the solubility and bioavailability of dutasteride (DUT). An NSC was loaded with DUT (dissolved in lipids) and dispersed at a nanoscale level using an entrapment technique. NSC…
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A clever combination galenIQ™ enhances the taste and formulation properties of vitamin D supplements Winter is here and the days are short. This means a lack of direct sunlight and, in turn, depleting levels of vitamin D in the body. In addition, owing to the coronavirus pandemic and recent…
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Determination of the granule density as a critical quality attribute during roller compaction/dry granulation provides an important parameter for further successful processing of the compacted materials. In this study, a novel approach was developed to determine the granule density using the…
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Mini-tablets are solid dosage forms with increasing interest for pharmaceutical industry due to clinical and biopharmaceutical benefits. But technological aspects on mini-tableting are not fully investigated. Therefore, the impact of punch size and tableting pressure for industrially relevant…
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Isupolish® FSC is a unique, dry milled, homogeneous blend of hypromellose, Isomalt or sucrose, pigments and additional excipients. Compared to a traditional sugar-coating process this product assists you to speed up the production process. An easy to use film-sugar-coating which can be applied by…
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The aim of the study was to formulate cilostazol containing nanosuspension by top-down wet milling method in order to increase the in vitro solubility and dissolution rate of this substance. The investigation of formulation parameters (emulsifier type, concentration, and combination of…
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