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Lactose
Lubricant Sensitivity of Direct Compression Grades of Lactose in Continuous and Batch Tableting…
Abstract
Modern pharmaceutical manufacturing based on Quality by Design and digitalisation is revolutionising the pharmaceutical industry. Continuous processes are promoted as they increase efficiency and improve quality control. Compared to batch blending, continuous blending is easier to scale…
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Comparison of Mini-Tablets and Pellets as Multiparticulate Drug Delivery Systems for Controlled Drug…
Mini-tablets made into hard capsules or administered using special dosing units, as well as pellets in hard capsules or compressed into tablets, offer the advantages of multiparticulate drug delivery systems and are suitable for controlled drug release using polymer coatings. Four different kinds of…
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Evaluation of the effect of granule size of raw tableting materials on critical quality attributes…
Abstract
Objective
The effects of granule size of raw materials on tablet hardness (TH) and weight (TW) in the continuous tablet manufacturing process (CTMP) were investigated using near-infrared spectroscopy (NIRS).
Methods
Granule materials of different sizes were prepared by extrusion…
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A dry powder formulation for peripheral lung delivery and absorption of an anti-SARS-CoV-2 ACE2…
One of the strategies proposed for the neutralization of SARS-CoV-2 has been to synthetize small proteins able to act as a decoy towards the virus spike protein, preventing it from entering the host cells. In this work, the incorporation of one of these proteins, LCB1, within a spray-dried…
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Neusilin Redefining Silica´s Potential in Solid Oral Dosage Forms
Neusilin
WHAT IS IT?
Neusilin® UFL2 is an ultra fine powder of magnesium aluminometasilicate and is widely accepted as a problem solving excipient for oral solid dosage forms.
Make harder tablets and protect it from humidity by adding 0.5-5% Neusilin® UFL2 to a lactose or mannitol…
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Comparative Evaluation of Particle Size Reduction, Salt Formation, and Amorphous Formulation on the…
Various approaches have been developed to enhance the solubility or dissolution rate for the delivery of poorly water-soluble molecules. In this work, guided by an in silico solubility sensitivity analysis for oral absorption, a comparative assessment of the biopharmaceutical performance of a…
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Selective anomer crystallization from aqueous solution: Monitoring lactose recovery under…
Lactose is typically produced via cooling crystallization either from whey(-permeate) (edible-grade) or from aqueous solution (pharmaceutical-grade). While in solution, lactose is present in 2 anomeric forms, α- and β-lactose. During cooling crystallization under standard process conditions, only…
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Lactalis Ingredients Pharma enters the excipients market with reliable pharmaceutical grade lactose
PRESS RELEASE
Our Story and Mission
Lactalis Ingredients was born with the certitude that every drop of milk is a source of innovation and inspiration. As an expert in high-value dairy ingredients with an experience of over 50 years, we developed a high technical and industrial expertise through…
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Leveraging a multivariate approach towards enhanced development of direct compression extended…
Extended release formulations play a crucial role in the pharmaceutical industry by maintaining steady plasma levels, reducing side effects, and improving therapeutic efficiency and compliance. One commonly used method to develop extended release formulations is direct compression, which offers…
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Uncovering advances in final end-user applications, user acceptability, quality assurance, and…
The increasing demand for innovative drugs and personalized treatment is radically changing the pharmaceutical industry, where significant efforts in research and development (R&D) are taking place. Three-dimensional (3D) printing offers interesting solutions for these demands, solving some of…
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