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Lipids
3D Printing Technology as a Promising Tool to Design Nanomedicine-Based Solid Dosage Forms:…
3D printing technology in medicine is gaining great attention from researchers since the FDA approved the first 3D-printed tablet (Spritam®) on the market. This technique permits the fabrication of various types of dosage forms with different geometries and designs. Its feasibility in the design of…
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Development of Orally Administrable Phytochemicals by Nano-Suspension and Nano-Emulsion Techniques
The awareness of the existence in plants of bioactive compounds namely phytochemicals (PHYs), having health properties is progressively expanding. Therefore, their massive introduction in the normal diet, in food supplements, and their use as natural therapeutics to treat several diseases are…
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Transferrin functionalized nanostructured lipid carriers for targeting Rivastigmine and Resveratrol…
The management of Alzheimer's disease (AD) remains challenging owing to its complex pathophysiology and blood-brain barrier (BBB) restrictions. A rationally designed combination drug multi-target strategy has emerged as a promising approach for AD management. Considering the lipophilic nature of BBB…
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Self-Nanoemulsifying Drug Delivery System for Enhanced Bioavailability of Madecassic Acid: In vitro…
Purpose: Madecassic acid (MCA) is a natural triterpenoid isolated from centellae herba that has diverse biological effects, such as anti-inflammatory, antioxidant, and anticancer activities. However, the efficacy of MCA is limited by low oral bioavailability caused by its extremely poor aqueous…
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Oral administration of Huanglian-Houpo herbal nanoemulsion loading multiple phytochemicals for…
How to achieve stable co-delivery of multiple phytochemicals is a common problem. This study focuses on the development, optimization and characterization of Huanglian-HouPo extract nanoemulsion (HLHPEN), with multiple components co-delivery, to enhance the anti-ulcerative colitis (UC) effects. The…
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Preformulation screening of lipids using solubility parameter concept in conjunction with…
Abstract
Development of ceftriaxone loaded nanostructured lipid carriers to increase permeability of ceftriaxone across uninflamed meninges after parenteral administration. Lipids were selected by theoretical and experimental techniques and optimization of NLCs done by response surface methodology…
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Recent advances in edible coating of food products and its legislations: A review
Abstract
Food products are highly perishable in nature which undergoes quick quality deterioration. In this note, the kind of packaging decides the active preservation of food qualities. Especially, edible coating plays a significant role in minimizing the post-harvest losses like moisture loss,…
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The Passive Diffusion Improvement of Vitamin B12 Intestinal Absorption by Gelucire that fit for…
Vitamin B12 (VB12) is a vital micronutrient to maintain the normal state of the hematopoietic system. It must be obtained from the diet since the human body cannot synthesize it. Moreover, the absorption of VB12 needs to be mediated by intrinsic factor on the gastrointestinal (GI) track. The…
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Design, Evaluation and Comparison of Nanostructured Lipid Carriers and Chitosan Nanoparticles as…
There is a serious need of pediatric drug formulations, whose lack causes the frequent use of extemporaneous preparations obtained from adult dosage forms, with consequent safety and quality risks. Oral solutions are the best choice for pediatric patients, due to administration ease and…
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Role of additives in starch-based edible films and coating: A review with current knowledge
Edible films and coating provide a potentially effective method for preserving fresh food products by reducing moisture loss, regulating respiration rate, improving surface smoothness, and or preventing microbial growth during their storage. Concurrently, starch has proven for its inexpensive,…
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