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Lipids
Benznidazole Self-Emulsifying Delivery System: A Novel Alternative Dosage Form For Chagas Disease…
Benznidazole (BZ) tablets are a unique form of treatment available for treating Chagas disease. Development of a liquid formulation containing BZ easy to administer orally for the treatment of paediatric patients, particularly for newborns is urgently required, with the same efficacy, safety and…
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Phase inversion-based nanoemulsions of medium chain triglyceride as potential drug delivery system…
Lipid nanoemulsions are attractive drug delivery systems for lipophilic drugs.
To produce nanoemulsions with droplets of very small diameter (<100 nm), we investigated thermotropic phase transitions as an alternative to the standard procedure of high-pressure homogenization. Employing shock…
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Critical steps during prilling process of molten lipids: main stumbling blocks due to pharmaceutical…
Prilling by ultrasonic jet break-up is an efficient process to produce perfectly spherical microparticles homogeneous in size.
However, the material properties could affect the manufacturability and the final product properties especially with lipid-based excipients which often exhibit complex…
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Formulation, optimization and in vitro evaluation of nanostructured lipid carriers for topical…
This work was aimed to formulate topical Apremilast loaded nanostructured lipid-carriers (NLCs) for the management of psoriasis.
Psoriasis is a widespread skin condition considered to be a Th1 autoimmune skin disease and characterized by excessive growth and abnormal differentiation of…
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Solid Lipid Nanoparticles: A Multidimensional Drug Delivery System
The development of drug delivery carriers is often very challenging, due to the physicochemical properties of the drug such as poor solubility, low permeability, and short half-life. Development of colloidal delivery systems has introduced new avenues for safe and effective drug delivery. However,…
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Formulation, optimization and in vitro evaluation of nanostructured lipid carriers for topical…
This work was aimed to formulate topical Apremilast loaded nanostructured lipid-carriers (NLCs) for the management of psoriasis.
Psoriasis is a widespread skin condition considered to be a Th1 autoimmune skin disease and characterized by excessive growth and abnormal differentiation of…
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Formulation Development and In Vitro Evaluation of Curcumin-Loaded Solid Self-Nanoemulsifying Drug…
Objective: Cancer is the deadliest disease affecting the life of the people all around the world. Colon cancer is the cancer which is affecting the colon region it is the last part of the gastrointestinal tract which is mainly responsible for the absorption of water and minerals from the food…
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Protective Effect of Saccharides on Freeze-Dried Liposomes Encapsulating Drugs
The production of freeze-dried liposomes encapsulating drugs is considered a key challenge since the drugs are prone to leakage.
The aim of this work was to study the effect of different saccharides on preserving the stability and drug retention capacity of a previously developed liposomal…
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Spray-dried liposomes: A study of the effect of carbohydrate carrier and concentrations on liposome…
Background and objective: Dry powder inhalation provide many promising features for
drug delivery to the pulmonary system, such as localization of drug within the lungs, drug
retention in the respiratory tract, and reduced systemic toxicities. This study aimed to
prepare dry powders of liposomes…
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Hydrogels as Potential Nano-, Micro- and Macro-Scale Systems for Controlled Drug Delivery
This review is an extensive evaluation and essential analysis of the design and formation of hydrogels (HGs) for drug delivery.
We review the fundamental principles of HGs (their chemical structures, physicochemical properties, synthesis routes, different types, etc.) that influence their…
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