Liquids

This review is an extensive evaluation and essential analysis of the design and formation of hydrogels (HGs) for drug delivery. We review the fundamental principles of HGs (their chemical structures, physicochemical properties, synthesis routes, different types, etc.) that influence their…
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This review is an extensive evaluation and essential analysis of the design and formation of hydrogels (HGs) for drug delivery. We review the fundamental principles of HGs (their chemical structures, physicochemical properties, synthesis routes, different types, etc.) that influence their…
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Liquid filling of hard gelatine capsules is an interesting approach to handle oily substances such as plant extracts incl. CBD in a better way. IN-CAP has become very popular all over the World among R&D Laboratories, Pharmacies, Hospitals, etc. for trials research, batch productions and in…
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Poly(vinyl acetate) – based matrix formulations are well known for obtaining strong sustained release functionality. Depending on the solubility of the active ingredient and the required dissolution profile, pore formers need to be added for adjusting drug release. The combination of both excellent…
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The bitter taste of caffeine can be a challenge especially in orally dispersible or liquid dosage forms. In both cases a taste masking by coating or encapsulation of the caffeine can be an effective way to achieve the desired result and increase the acceptance of the final product. Micro…
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In spite of the major advantages that the liquisolid technology offers, particularly in tackling poor bioavailability of poorly water-soluble drugs (i.e., BCS Class II drugs), there are a few critical drawbacks. The inability of a high liquid load factor, poor flowability, poor compactibility,…
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Azithromycin (AZI) eye drops containing sodium hyaluronate (SH) were developed to improve the bioavailability of AZI. Interaction between AZI and SH in the AZI-SH formulation was investigated by differential scanning calorimetry, X-ray diffraction, and 1H-nuclear magnetic resonance spectroscopy…
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Spray drying biologics and small-molecule drugs can increase their thermal stability relative to liquid dosage forms and allow for widespread distribution to developing countries without cold chain infrastructure. In this study, pullulan trehalose powder is spray dried for inhalation. The powder…
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Quercus Suber Bark from Quercus suber L. is a natural, renewable and biodegradable biomaterial with multifunctional proprieties. In this study, we used it as solid particles to stabilize a Pickering emulsion. The main goal was to produce an optimized topical formulation using biocompatible organic…
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The present research work describes the formulation development of liquisolid compact tablets of pioglitazone for improving its dissolution performance and antidiabetic activity. Using Quality by Design (QbD) approach, a total of nine formulations were prepared as per the central composite design…
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