Pharma Excipients
Liquids
The central role of excipients in drug formulation
Active substances are rarely administered alone. For example, levothyroxine, a synthetic form of the thyroid hormone, indicated in the treatment of hypothyroidism, is administered at a very low dosage, ranging from 15 μg to 200 μg. These very small amounts of powder mean that it is not possible…
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Syloid® XDP silica – New Application Note on Solid delivery of PEG drug solubilizers –…
22. September 2015
Syloid® XDP silica: Carrier for liquid drug solubilizers in solid dosage form.
The solubility of poorly soluble drugs can be increased by using solubilizers such as polyethylene glycols (PEG), Tween 80 etc. These solublizers can be used to increase oral bioavailability…
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FORMULATION DEVELOPMENT – A QbD Approach to Develop Extended Release Softgels
31. March 2015
Soft gelatin capsules (softgels) continue to be the oral solid dosage form preferred by consumers.1 Understandably, as they are easy to swallow and digest, effectively mask unpleasant tastes and smells, and have a pleasing appearance. Softgels also offer formulation and marketing…
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A Self-microemulsifying Drug Delivery System (SMEDDS) for a Novel Medicative Compound Against…
08. February 2015
AJS is the code name of an untitled novel medicative compound synthesized by the Tasly Holding Group Company (Tianjin, China) based on the structure of cinnamamide, which is one of the Biopharmaceutics Classification System (BCS) class II drugs. The drug has…
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Capsugel Advances the First Intrinsically Enteric Capsule Technology
Capsugel is a global leader in delivering high-quality, innovative dosage forms and solutions to its customers in the health care industry. The company’s Hard Capsule business unit offers customers the broadest portfolio of gelatin, vegetarian and other specialized capsule…
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