Lubricant excipients are substances that are added to tablet formulations to aid in the tableting process and to improve the flow of powders during the manufacturing of tablets. These excipients reduce friction and prevent the sticking of the tablet material to the surface of the die and punches, allowing for smoother tablet production and reducing the wear and tear on the tableting equipment.
Pharma Excipients
Lubricant
Tablet ejection force and its sensitivity to lubrication for pharmaceutical powders
09. April 2018 Pharmaceutical powders can exhibit markedly different tablet ejection forces. The purpose of this study is to understand the factors leading to the variability of the tablet ejection force and its sensitivity to…
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Systematic evaluation of common lubricants for optimal use in tablet formulation
26. February 2018 As an essential formulation component for large-scale tablet manufacturing, the lubricant preserves tooling by reducing die-wall friction. Unfortunately, lubrication also often results in adverse effects on…
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Evaluation of lubricants for optimal use in tablets
13. February 2018 Abstract As an essential formulation component for large-scale tablet manufacturing, the lubricant preserves tooling by reducing die-wall friction. Unfortunately, lubrication also often results in adverse…
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Influence of lubrication and particle size distribution effects on tablet characteristics
16. January 2018 Abstract We adopt a Quality by Design (QbD) paradigm to better control the mechanical properties of tablets. To this end, the effect of particle size distribution, lubricant concentration, and mixing time on…
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Lubricant based determination of design space for continuously manufactured high dose paracetamol…
30. December 2017 Abstract The objective of this study was to devise robust and stable continuous manufacturing process settings, by exploring the design space after an investigation of the lubrication-based parameters…
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Controlled shear system and resonant acoustic mixing
13. October 2017 Purpose Lubrication is critical in pharmaceutical manufacturing of solid dosage forms. The purpose of this paper is to systematically compare and correlate the lubrication effect of two devices, a…
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Mixing by Controlled shear system and resonant acoustic: Effects on lubrication and flow properties
26. September 2017 Purpose Lubrication is critical in pharmaceutical manufacturing of solid dosage forms. The purpose of this paper is to systematically compare and correlate the lubrication effect of two devices, a controlled…
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Effect of the External Lubrication Method for a Rotary Tablet Press on the Adhesion of the Film…
06. September 2017 Abstract External lubrication is a useful method which reduces the adhesion of powder to punches and dies by spraying lubricants during the tableting process.…
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How to reduce the risk of tablet picking and sticking
23. May 2017 Summary Poor lubrication results in picking and sticking problems during production. These are one of the most common causes of tablet defects which result in slow running of the tablet press and reduced output.…
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LubriTose™ PB The Ideal Choice for Placebo Manufacturing without the Mixing
07. April 2017
LubriTose™ PB The Ideal Choice for Placebo Manufacturing without the Mixing
Key benefits
• Enables dispensing straight from the drum to the hopper
• Eliminates any need for external lubricant
• Placebos provided optimal substrates for film…
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