Magnesium stearate, also known as magnesium octadecanoate, is a common additive used in the pharmaceutical industry. It is a white, odorless, and tasteless powder that is highly insoluble in water, but soluble in organic solvents.
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Magnesium Stearate
The Utilization of Surface Free Energy for Predicting Flowability of Filler-Lubricant or…
31. January 2017
The aim of this study was to apply the knowledge of surface free energy for the flowability prediction of pharmaceutical excipients. In order to predict the flowability, the spreading coefficient was calculated from the surface free energy of each material using Wu's…
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Solid State Interactions Between Ketoprofen and Excipients in Solid Dosage Forms
08. November 2016
This study assesses the solid-solid interactions between the commercial form of Ketoprofen (KET), a non- steroidal anti-inflammatory drug of the propionic acid class, and several widely used pharmaceutical excipients. The work was carried out on drug-excipient…
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Design and Evaluation of Solubility Enhancement of Poorly Soluble Drugs using Liquid Solid Compacts
30. September 2016
ABSTRACT
Oral dosage form is the physical form of a dose of a chemical compound used as a drug or medication intended for administration or consumption by the oral route. The poor dissolution rate of water insoluble drugs is still a substantial problem…
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Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classification System…
31. March 2016
The objective was to assess the impact of larger than conventional amounts of 14 commonly used excipients on Biopharmaceutics Classification System (BCS) class 3 drug absorption in humans. Cimetidine and acyclovir were used as model class 3 drugs across three separate…
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Lubricants in Pharmaceutical Solid Dosage Forms
Lubrication plays a key role in successful manufacturing of pharmaceutical solid dosage forms; lubricants are essential ingredients in robust formulations to achieve this. Although many failures in pharmaceutical manufacturing operations are caused by issues related to lubrication, in…
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13C solid-state NMR analysis of the most common pharmaceutical excipients used in solid drug…
Excipients used in the solid drug formulations differ in their NMR relaxation and 13C cross-polarization (CP) kinetics parameters. Therefore, experimental parameters like contact time of cross-polarization and repetition time have a major impact on the registered solid state NMR spectra and in…
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Magnesium Stearate US Pharmacopeial Convention -Notice of Adoption of Harmonized Standard
28. September 2015
The correction to the harmonized standard for Magnesium Stearate has been approved by the Pharmacopeial Discussion Group (PDG) as described in its PDG sign-off cover sheet. Having reached Stage 6 of the PDG process, the Magnesium Stearate monograph has been…
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