Magnesium stearate, also known as magnesium octadecanoate, is a common additive used in the pharmaceutical industry. It is a white, odorless, and tasteless powder that is highly insoluble in water, but soluble in organic solvents.
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Magnesium Stearate
Taste Masked Artesunate/Amodiaquine Micropellets in the Fight Against Malaria
This article shows the content of a poster which was presented at the 𝗘𝗨𝗣𝗳𝗜 𝗰𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗶𝗻 𝗚𝗹𝗮𝘀𝗴𝗼𝘄 2023
Malaria & Treatment Challenges
Children aged under 5 years are the worst affected by malaria, causing about 10 % of all children’s deaths in regions where malaria is endemic. Fixed dose…
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The effect of polymeric binder type and concentration on flow and dissolution properties of SMEDDS…
Self-microemulsifying drug delivery systems (SMEDDS) are lipid-based formulations, designed to improve the solubility of poorly-water soluble drugs. Mesoporous silica is frequently used for SMEDDS solidification by various techniques. One of them is wet granulation, which enables achieving both high…
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Comparison of properties on Orally Disintegrating Tablets (ODTs) produced by direct compression or…
Abstract
Orally disintegrating tablets (ODTs) is a popular drug delivery system as they dissolve in the mouth, usually within seconds which enables easy medication for patients with problem swallowing. In this thesis properties of ODTs were compared when produced with direct compression of the…
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Indices for the brittleness of pharmaceutical tablets: a reassessment
Brittleness is an important mechanical property. In the classical sense, a material is considered brittle if, during loading, it behaves elastically until failure. Nevertheless, it is also sometimes understood as the fact to be resistant to breakage. In the case of pharmaceutical tablets, three…
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Effect of geometrical features on the capping behavior of biconvex tablets
Abstract
Capping is a common industrial issue during the manufacturing of pharmaceutical tablets. It is influenced by both process and formulation parameters. In this work, a systematic study of the influence of the geometrical features of biconvex tablets on capping occurrence was performed on a…
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HiCel™ Silicified Microcrystalline Cellulose, Versatile Excipient for Nutraceutical Herbal Tablet…
Abstract
Nutraceutical herbal medicine and supplements demand increases day by day. Herbal medicine normally contains lipids, protein, carbohydrate, vitamins, minerals and other necessary nutrients depending upon their emphases. Generally, all herbal extracts powder nature is fine poor flowable,…
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Effects of Granulated Lactose Characteristics and Lubricant Blending Conditions on Tablet Physical…
Abstract
Lactose is an excipient used extensively for bulking, diluting, and molding active pharmaceutical ingredients in tablet manufacturing. Particularly, granulated lactose (GL) intended for direct powder compression has distinct properties due to differences in manufacturing methods. It…
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Hot Melt Extrusion for Improving the Physicochemical Properties of Polydatin Derived from Polygoni…
Abstract
Three different types of solid dispersions based on polyvinyl polymers and related copolymers (Kollidon® VA64, Soluplus® and Kollicoat IR®) comprising polydatin-rich Polygoni cuspidati extract were prepared by hot melt extrusion. The systems were characterized using X-ray powder…
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Comparing the Performance of Raman and Near-Infrared Imaging in the Prediction of the In Vitro…
In this work, the performance of two fast chemical imaging techniques, Raman and near-infrared (NIR) imaging is compared by utilizing these methods to predict the rate of drug release from sustained-release tablets. Sustained release is provided by adding hydroxypropyl methylcellulose (HPMC), as its…
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Effect of Compaction Pressure on the Enzymatic Activity of Pancreatin in Directly Compressible…
Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated. In the present study, pancreatin was employed as a model enzyme mixture, which was formulated in tablet…
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