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Maltodextrin
Hydration and dehydration induced changes in porosity of starch microspheres
Characterization and tuning of the porosity of amorphous starch materials are important for many applications, including controlled release of encapsulated proteins. The porosities of these materials in dry and hydrated states can have different physicochemical origins and properties. Here,…
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Percolation-based simulation to predict caking kinetics of polydisperse amorphous powders
Caking in amorphous powders compromises their quality during storage. Individual particles absorb water vapor, which changes their viscosity and promotes the formation of sinter bridges. Lumps of particles grow and eventually span the whole powder, affecting the mechanical properties and quality of…
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Spray Drying for Direct Compression of Pharmaceuticals
Tableting by direct compression (DC) is one of the simplest and most cost-effective drug manufacturing approaches. However, most active pharmaceutical ingredients (APIs) and excipients lack the compression and flow properties required to meet the needs of high-speed industrial tablet presses.…
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What is the Role of Over 100 Excipients in Over the Counter (OTC) Cough Medicines?
by Eccles, R. What is the Role of Over 100 Excipients in Over the Counter (OTC) Cough Medicines?. Lung (2020). https://doi.org/10.1007/s00408-020-00390-x
Most medicines are white bitter powders that are formulated as tablets and capsules but cough medicines are an exception where the taste and…
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Erodible Coatings Based on HPMC and Cellulase for Oral Time-Controlled Release of Drugs
Oral drug delivery systems for time-controlled release, intended for chronotherapy or colon targeting, are often in the form of coated dosage forms provided with swellable/soluble hydrophilic polymer coatings. The latter are responsible for programmable lag phases prior to release, due to their…
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